| pubmed-article:18656208 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18656208 | lifeskim:mentions | umls-concept:C0001779 | lld:lifeskim |
| pubmed-article:18656208 | lifeskim:mentions | umls-concept:C1412481 | lld:lifeskim |
| pubmed-article:18656208 | lifeskim:mentions | umls-concept:C1862941 | lld:lifeskim |
| pubmed-article:18656208 | lifeskim:mentions | umls-concept:C0004083 | lld:lifeskim |
| pubmed-article:18656208 | lifeskim:mentions | umls-concept:C0332162 | lld:lifeskim |
| pubmed-article:18656208 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:18656208 | pubmed:dateCreated | 2008-9-1 | lld:pubmed |
| pubmed-article:18656208 | pubmed:abstractText | Amyotrophic lateral sclerosis (ALS) is a neurodegenerative syndrome with familial and sporadic forms. We conducted a study including 60 sporadic and 19 familial ALS patients, 206 reference patients with other neurological disorders and 1265 neurologically healthy controls to assess the Alzheimer-associated apolipoprotein E (APOE) epsilon4 gene variant as a possible risk factor for ALS. While no major influence of APOE epsilon4 on disease risk was detected, a gene dose-dependent effect with lower age at onset of sporadic ALS in epsilon4 carriers was found (p=0.027). These data support APOE epsilon4 as a subordinate contributing factor in ALS. | lld:pubmed |
| pubmed-article:18656208 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18656208 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18656208 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18656208 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18656208 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18656208 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18656208 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18656208 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:18656208 | pubmed:issn | 0022-510X | lld:pubmed |
| pubmed-article:18656208 | pubmed:author | pubmed-author:BlennowKajK | lld:pubmed |
| pubmed-article:18656208 | pubmed:author | pubmed-author:RosengrenLars... | lld:pubmed |
| pubmed-article:18656208 | pubmed:author | pubmed-author:AndersenPeter... | lld:pubmed |
| pubmed-article:18656208 | pubmed:author | pubmed-author:ZetterbergHen... | lld:pubmed |
| pubmed-article:18656208 | pubmed:author | pubmed-author:JacobssonJoha... | lld:pubmed |
| pubmed-article:18656208 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:18656208 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:18656208 | pubmed:volume | 273 | lld:pubmed |
| pubmed-article:18656208 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18656208 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18656208 | pubmed:pagination | 67-9 | lld:pubmed |
| pubmed-article:18656208 | pubmed:meshHeading | pubmed-meshheading:18656208... | lld:pubmed |
| pubmed-article:18656208 | pubmed:meshHeading | pubmed-meshheading:18656208... | lld:pubmed |
| pubmed-article:18656208 | pubmed:meshHeading | pubmed-meshheading:18656208... | lld:pubmed |
| pubmed-article:18656208 | pubmed:meshHeading | pubmed-meshheading:18656208... | lld:pubmed |
| pubmed-article:18656208 | pubmed:meshHeading | pubmed-meshheading:18656208... | lld:pubmed |
| pubmed-article:18656208 | pubmed:meshHeading | pubmed-meshheading:18656208... | lld:pubmed |
| pubmed-article:18656208 | pubmed:meshHeading | pubmed-meshheading:18656208... | lld:pubmed |
| pubmed-article:18656208 | pubmed:meshHeading | pubmed-meshheading:18656208... | lld:pubmed |
| pubmed-article:18656208 | pubmed:meshHeading | pubmed-meshheading:18656208... | lld:pubmed |
| pubmed-article:18656208 | pubmed:meshHeading | pubmed-meshheading:18656208... | lld:pubmed |
| pubmed-article:18656208 | pubmed:meshHeading | pubmed-meshheading:18656208... | lld:pubmed |
| pubmed-article:18656208 | pubmed:meshHeading | pubmed-meshheading:18656208... | lld:pubmed |
| pubmed-article:18656208 | pubmed:meshHeading | pubmed-meshheading:18656208... | lld:pubmed |
| pubmed-article:18656208 | pubmed:meshHeading | pubmed-meshheading:18656208... | lld:pubmed |
| pubmed-article:18656208 | pubmed:meshHeading | pubmed-meshheading:18656208... | lld:pubmed |
| pubmed-article:18656208 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18656208 | pubmed:articleTitle | Association of APOE with age at onset of sporadic amyotrophic lateral sclerosis. | lld:pubmed |
| pubmed-article:18656208 | pubmed:affiliation | Department of Neurochemistry and Psychiatry, Sahlgrenska University Hospital, Göteborg University, Sweden. henrik.zetterberg@clinchem.gu.se | lld:pubmed |
| pubmed-article:18656208 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18656208 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:348 | entrezgene:pubmed | pubmed-article:18656208 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:18656208 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18656208 | lld:pubmed |
