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pubmed-article:18639867pubmed:abstractTextClinical observations suggest that cocaine addiction often emerges with new patterns of use. Whether these changes are a cause of addiction or its consequence is unknown. We investigated whether the development of an addiction-like behavior in the rat is associated with the pattern of cocaine intake and with cocaine craving, a major feature of cocaine addiction.lld:pubmed
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pubmed-article:18639867pubmed:articleTitlePattern of intake and drug craving predict the development of cocaine addiction-like behavior in rats.lld:pubmed
pubmed-article:18639867pubmed:affiliationCRI U862, Physiopathologie de l'addiction, Institut François Magendie, Bordeaux Cedex 33077, France.lld:pubmed
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