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pubmed-article:18631172pubmed:issue6lld:pubmed
pubmed-article:18631172pubmed:dateCreated2009-11-13lld:pubmed
pubmed-article:18631172pubmed:abstractTextThe objective of this study was to establish haematological reference ranges for the West African subregion using a Gambian cohort. We analysed full blood counts from 1279 subjects aged > or =1 year. Anthropometric and body composition measurements were performed. Haematological mean values, medians and 90% reference values were calculated and related to malnutrition in children and thinness and/or obesity in adults. Haemoglobin (Hb) and mean corpuscular volume (MCV) significantly increased with age (P < 0.00001). There were gender-related changes in Hb from 15 years of age (P = 0.001) and for MCV only in adults (P = 0.0002). Hb was significantly reduced in underweight and stunted children (P = 0.0001 and 0.0002, respectively) but was unaffected by thinness or obesity in adults. White blood cell (WBC) and platelet counts were highest under 5 years and declined significantly with age (P < 0.0001 and 0.0001). While, there were no gender-related differences with WBC, there were higher WBC counts in underweight (P = 0.0001) and stunted (P < 0.0001) children. Adult females had significantly higher mean platelet counts compared with males (P = 0.006). The mean and median values of haematological parameters in The Gambia are similar to other standards but the 90% reference range for each parameter encompasses lower values when compared with Western standards.lld:pubmed
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pubmed-article:18631172pubmed:authorpubmed-author:JeffriesD JDJlld:pubmed
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pubmed-article:18631172pubmed:authorpubmed-author:AdetifaI M...lld:pubmed
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pubmed-article:18631172pubmed:volume31lld:pubmed
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pubmed-article:18631172pubmed:pagination615-22lld:pubmed
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pubmed-article:18631172pubmed:year2009lld:pubmed
pubmed-article:18631172pubmed:articleTitleHaematological values from a Gambian cohort--possible reference range for a West African population.lld:pubmed
pubmed-article:18631172pubmed:affiliationBacterial Diseases Programme, Medical Research Council (UK) Laboratories, The Gambia. iadetifa@mrc.gmlld:pubmed
pubmed-article:18631172pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:18631172pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed