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pubmed-article:18627359pubmed:abstractTextAddiction has been considered a disorder of motivational control over behavior, and the ventral tegmental area (VTA), in conjunction with other limbic brain structures, is thought to play a critical role in the regulation of a number of motivated behaviors including seeking of addictive drugs such as alcohol. Of particular interest is the ability of prolonged exposure of addictive drugs to enhance the function of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamatergic receptors (AMPAR) in the VTA, as glutamate receptor activation can significantly regulate VTA neuron activity. Here, we examined whether voluntary ethanol intake altered VTA AMPAR function.lld:pubmed
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pubmed-article:18627359pubmed:articleTitleVoluntary ethanol intake enhances excitatory synaptic strength in the ventral tegmental area.lld:pubmed
pubmed-article:18627359pubmed:affiliationDepartment of Neurology, Ernest Gallo Clinic and Research Center, University of California at San Francisco, Emeryville, California 94608, USA.lld:pubmed
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