pubmed-article:1862660 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:1862660 | lifeskim:mentions | umls-concept:C0032098 | lld:lifeskim |
pubmed-article:1862660 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
pubmed-article:1862660 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
pubmed-article:1862660 | lifeskim:mentions | umls-concept:C0026336 | lld:lifeskim |
pubmed-article:1862660 | lifeskim:mentions | umls-concept:C0025519 | lld:lifeskim |
pubmed-article:1862660 | lifeskim:mentions | umls-concept:C0043335 | lld:lifeskim |
pubmed-article:1862660 | lifeskim:mentions | umls-concept:C0870883 | lld:lifeskim |
pubmed-article:1862660 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:1862660 | pubmed:dateCreated | 1991-8-30 | lld:pubmed |
pubmed-article:1862660 | pubmed:abstractText | 1. The metabolism of a model xenobiotic plant metabolite S-benzyl-N-malonyl-L-cysteine (BMC) administered to rat at 10 mg/kg has been studied using a combination of radio-t.l.c. and h.p.l.c. 2. The major route of excretion for the administered 14C was via the urine (79% in 3 days). 3. The major metabolite was hippuric acid. The extent of biotransformation of BMC indicated the lability of the N-malonyl bond whose hydrolytic removal initiated a metabolic sequence which involved the action of C-S lyase to produce benzyl thiol. 4. A comparison of the findings from this study with those from experiments with N-acetyl-S-benzyl-L-cysteine and S-benzyl-L-cysteine is made to support the metabolic pathway proposed. | lld:pubmed |
pubmed-article:1862660 | pubmed:language | eng | lld:pubmed |
pubmed-article:1862660 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1862660 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:1862660 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1862660 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1862660 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1862660 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:1862660 | pubmed:month | Mar | lld:pubmed |
pubmed-article:1862660 | pubmed:issn | 0049-8254 | lld:pubmed |
pubmed-article:1862660 | pubmed:author | pubmed-author:HutsonD HDH | lld:pubmed |
pubmed-article:1862660 | pubmed:author | pubmed-author:JonesB CBC | lld:pubmed |
pubmed-article:1862660 | pubmed:author | pubmed-author:RichardsonK... | lld:pubmed |
pubmed-article:1862660 | pubmed:author | pubmed-author:EdwardsV TVT | lld:pubmed |
pubmed-article:1862660 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:1862660 | pubmed:volume | 21 | lld:pubmed |
pubmed-article:1862660 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:1862660 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:1862660 | pubmed:pagination | 371-82 | lld:pubmed |
pubmed-article:1862660 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:1862660 | pubmed:meshHeading | pubmed-meshheading:1862660-... | lld:pubmed |
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pubmed-article:1862660 | pubmed:meshHeading | pubmed-meshheading:1862660-... | lld:pubmed |
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pubmed-article:1862660 | pubmed:meshHeading | pubmed-meshheading:1862660-... | lld:pubmed |
pubmed-article:1862660 | pubmed:meshHeading | pubmed-meshheading:1862660-... | lld:pubmed |
pubmed-article:1862660 | pubmed:year | 1991 | lld:pubmed |
pubmed-article:1862660 | pubmed:articleTitle | Metabolism in the rat of a model xenobiotic plant metabolite S-benzyl-N-malonyl-L-cysteine. | lld:pubmed |
pubmed-article:1862660 | pubmed:affiliation | Shell Research Ltd, Sittingbourne Research Centre, Kent, UK. | lld:pubmed |
pubmed-article:1862660 | pubmed:publicationType | Journal Article | lld:pubmed |