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pubmed-article:18609162pubmed:abstractTextSevere acute pancreatitis (SAP) frequently progresses to pancreatitis-associated multiorgan failure (MOF) with high mortality. Decreased plasma ADAMTS13 activity (ADAMTS13:AC) results in the accumulation of unusually large von Willebrand factor multimers (UL-VWFM) and the formation of platelet thrombi, ultimately leading to MOF. The purpose of the study was to investigate the potential role of ADAMTS13:AC in the severity of SAP.lld:pubmed
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pubmed-article:18609162pubmed:articleTitlePlasma ADAMTS13 activity parallels the APACHE II score, reflecting an early prognostic indicator for patients with severe acute pancreatitis.lld:pubmed
pubmed-article:18609162pubmed:affiliationThird Department of Internal Medicine, Nara Medical University, Kashihara, Nara, Japan.lld:pubmed
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