| pubmed-article:18502330 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18502330 | lifeskim:mentions | umls-concept:C0007115 | lld:lifeskim |
| pubmed-article:18502330 | lifeskim:mentions | umls-concept:C0026882 | lld:lifeskim |
| pubmed-article:18502330 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:18502330 | pubmed:dateCreated | 2008-5-26 | lld:pubmed |
| pubmed-article:18502330 | pubmed:abstractText | The close genotype-phenotype relationship that characterizes thyroid oncology stimulated the authors to address this article by using a mixed, genetic and phenotypic approach. As such, this article addresses the following aspects of intragenic mutations in thyroid cancer: thyroid stimulating hormone receptor and guanine-nucleotide-binding proteins of the stimulatory family mutations in hyperfunctioning tumors; mutations in RAS and other genes and aneuploidy; PAX8-PPARgamma rearrangements; BRAF mutations; mutations in oxidative phosphorylation and Krebs cycle genes in Hürthle cell tumors; mutations in succinate dehydrogenase genes in medullary carcinoma and C-cell hyperplasia; and mutations in TP53 and other genes in poorly differentiated and anaplastic carcinomas. | lld:pubmed |
| pubmed-article:18502330 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18502330 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18502330 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:18502330 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18502330 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:18502330 | pubmed:issn | 0889-8529 | lld:pubmed |
| pubmed-article:18502330 | pubmed:author | pubmed-author:Sobrinho-Simõ... | lld:pubmed |
| pubmed-article:18502330 | pubmed:author | pubmed-author:SoaresPaulaP | lld:pubmed |
| pubmed-article:18502330 | pubmed:author | pubmed-author:MáximoValdema... | lld:pubmed |
| pubmed-article:18502330 | pubmed:author | pubmed-author:LimaJorgeJ | lld:pubmed |
| pubmed-article:18502330 | pubmed:author | pubmed-author:CastroPatrici... | lld:pubmed |
| pubmed-article:18502330 | pubmed:author | pubmed-author:PretoAnaA | lld:pubmed |
| pubmed-article:18502330 | pubmed:author | pubmed-author:RochaAna... | lld:pubmed |
| pubmed-article:18502330 | pubmed:author | pubmed-author:TroviscoVitor... | lld:pubmed |
| pubmed-article:18502330 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:18502330 | pubmed:volume | 37 | lld:pubmed |
| pubmed-article:18502330 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18502330 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18502330 | pubmed:pagination | 333-62, viii | lld:pubmed |
| pubmed-article:18502330 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:18502330 | pubmed:meshHeading | pubmed-meshheading:18502330... | lld:pubmed |
| pubmed-article:18502330 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18502330 | pubmed:articleTitle | Intragenic mutations in thyroid cancer. | lld:pubmed |
| pubmed-article:18502330 | pubmed:affiliation | Institute of Molecular Pathology and Immunology of the University of Porto, Rua Roberto Frias s/n, 4200-465 Porto, Portugal. | lld:pubmed |
| pubmed-article:18502330 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18502330 | pubmed:publicationType | Review | lld:pubmed |
| pubmed-article:18502330 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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