| pubmed-article:18483286 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18483286 | lifeskim:mentions | umls-concept:C0054594 | lld:lifeskim |
| pubmed-article:18483286 | lifeskim:mentions | umls-concept:C0007114 | lld:lifeskim |
| pubmed-article:18483286 | lifeskim:mentions | umls-concept:C0021368 | lld:lifeskim |
| pubmed-article:18483286 | lifeskim:mentions | umls-concept:C1527148 | lld:lifeskim |
| pubmed-article:18483286 | lifeskim:mentions | umls-concept:C1546857 | lld:lifeskim |
| pubmed-article:18483286 | lifeskim:mentions | umls-concept:C1556066 | lld:lifeskim |
| pubmed-article:18483286 | lifeskim:mentions | umls-concept:C1619636 | lld:lifeskim |
| pubmed-article:18483286 | lifeskim:mentions | umls-concept:C1514873 | lld:lifeskim |
| pubmed-article:18483286 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:18483286 | pubmed:dateCreated | 2008-5-16 | lld:pubmed |
| pubmed-article:18483286 | pubmed:abstractText | Solar UV irradiation is an important carcinogen that leads to the development of skin cancer, which is the most common human cancer. However, the receptors that mediate UV-induced skin carcinogenesis have not yet been unequivocally identified. Here we showed that UV irradiation directly activates cannabinoid receptors 1 and 2 (CB1/2). Notably, our data indicated that the absence of the CB1/2 receptors in mice results in a dramatic resistance to UVB-induced inflammation and a marked decrease in UVB-induced skin carcinogenesis. A marked attenuation of UVB-induced activation of mitogen-activated protein kinases and nuclear factor- kappaB was associated with CB1/2 deficiency. These data provide direct evidence indicating that the CB1/2 receptors play a key role in UV-induced inflammation and skin cancer development. | lld:pubmed |
| pubmed-article:18483286 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18483286 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18483286 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18483286 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18483286 | pubmed:month | May | lld:pubmed |
| pubmed-article:18483286 | pubmed:issn | 1538-7445 | lld:pubmed |
| pubmed-article:18483286 | pubmed:author | pubmed-author:MaWei-YaWY | lld:pubmed |
| pubmed-article:18483286 | pubmed:author | pubmed-author:BodeAnn MAM | lld:pubmed |
| pubmed-article:18483286 | pubmed:author | pubmed-author:DongZigangZ | lld:pubmed |
| pubmed-article:18483286 | pubmed:author | pubmed-author:ZhuFengF | lld:pubmed |
| pubmed-article:18483286 | pubmed:author | pubmed-author:ZhengDuoD | lld:pubmed |
| pubmed-article:18483286 | pubmed:author | pubmed-author:ZhaoQingQ | lld:pubmed |
| pubmed-article:18483286 | pubmed:author | pubmed-author:ChoYong-YeonY... | lld:pubmed |
| pubmed-article:18483286 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:18483286 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:18483286 | pubmed:volume | 68 | lld:pubmed |
| pubmed-article:18483286 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18483286 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18483286 | pubmed:pagination | 3992-8 | lld:pubmed |
| pubmed-article:18483286 | pubmed:dateRevised | 2010-12-3 | lld:pubmed |
| pubmed-article:18483286 | pubmed:meshHeading | pubmed-meshheading:18483286... | lld:pubmed |
| pubmed-article:18483286 | pubmed:meshHeading | pubmed-meshheading:18483286... | lld:pubmed |
| pubmed-article:18483286 | pubmed:meshHeading | pubmed-meshheading:18483286... | lld:pubmed |
| pubmed-article:18483286 | pubmed:meshHeading | pubmed-meshheading:18483286... | lld:pubmed |
| pubmed-article:18483286 | pubmed:meshHeading | pubmed-meshheading:18483286... | lld:pubmed |
| pubmed-article:18483286 | pubmed:meshHeading | pubmed-meshheading:18483286... | lld:pubmed |
| pubmed-article:18483286 | pubmed:meshHeading | pubmed-meshheading:18483286... | lld:pubmed |
| pubmed-article:18483286 | pubmed:meshHeading | pubmed-meshheading:18483286... | lld:pubmed |
| pubmed-article:18483286 | pubmed:meshHeading | pubmed-meshheading:18483286... | lld:pubmed |
| pubmed-article:18483286 | pubmed:meshHeading | pubmed-meshheading:18483286... | lld:pubmed |
| pubmed-article:18483286 | pubmed:meshHeading | pubmed-meshheading:18483286... | lld:pubmed |
| pubmed-article:18483286 | pubmed:meshHeading | pubmed-meshheading:18483286... | lld:pubmed |
| pubmed-article:18483286 | pubmed:meshHeading | pubmed-meshheading:18483286... | lld:pubmed |
