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pubmed-article:18414391pubmed:abstractTextInhibition of proteasome has been emerging as a promising approach in pathway-directed cancer therapy. Bone morphogenetic protein (BMP) signalling, which is known to be regulated by the ubiquitin-proteasome pathway in osteoblasts, plays a crucial role in the suppression of gastrointestinal carcinogenesis. Here we sought to elucidate the anti-mitogenic effect of a proteasome inhibitor in relation to BMP signalling in colon cancer.lld:pubmed
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pubmed-article:18414391pubmed:articleTitleBone morphogenetic protein signalling is required for the anti-mitogenic effect of the proteasome inhibitor MG-132 on colon cancer cells.lld:pubmed
pubmed-article:18414391pubmed:affiliationDepartment of Medicine & Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.lld:pubmed
pubmed-article:18414391pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:18414391pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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