| pubmed-article:18367480 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18367480 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:18367480 | lifeskim:mentions | umls-concept:C1171350 | lld:lifeskim |
| pubmed-article:18367480 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:18367480 | lifeskim:mentions | umls-concept:C0205198 | lld:lifeskim |
| pubmed-article:18367480 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:18367480 | pubmed:dateCreated | 2008-5-2 | lld:pubmed |
| pubmed-article:18367480 | pubmed:abstractText | Resistance to imatinib is an important clinical issue in the treatment of Philadelphia chromosome-positive leukemias which is being tackled by the development of new, more potent drugs, such as the dual Src/Abl tyrosine kinase inhibitors dasatinib and bosutinib and the imatinib analog nilotinib. In the current study we describe the design, synthesis and biological properties of an imatinib analog with a chlorine-substituted benzamide, namely compound 584 (cmp-584). | lld:pubmed |
| pubmed-article:18367480 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18367480 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18367480 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18367480 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:18367480 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18367480 | pubmed:month | May | lld:pubmed |
| pubmed-article:18367480 | pubmed:issn | 1592-8721 | lld:pubmed |
| pubmed-article:18367480 | pubmed:author | pubmed-author:ClerisLoredan... | lld:pubmed |
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| pubmed-article:18367480 | pubmed:author | pubmed-author:Donella-Deana... | lld:pubmed |
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| pubmed-article:18367480 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:18367480 | pubmed:volume | 93 | lld:pubmed |
| pubmed-article:18367480 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18367480 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18367480 | pubmed:pagination | 653-61 | lld:pubmed |
| pubmed-article:18367480 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:18367480 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18367480 | pubmed:articleTitle | Characterization of compound 584, an Abl kinase inhibitor with lasting effects. | lld:pubmed |
| pubmed-article:18367480 | pubmed:affiliation | School of Pharmaceutical Sciences, University of Geneva, Quai Ernest-Ansermet 30, 1211 Genève 4, Switzerland. | lld:pubmed |
| pubmed-article:18367480 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18367480 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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