Linked Life Data

18348074

Source:http://linkedlifedata.com/resource/pubmed/id/18348074

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:18348074rdf:typepubmed:Citationlld:pubmed
pubmed-article:18348074lifeskim:mentionsumls-concept:C1123023lld:lifeskim
pubmed-article:18348074lifeskim:mentionsumls-concept:C0023828lld:lifeskim
pubmed-article:18348074lifeskim:mentionsumls-concept:C0205360lld:lifeskim
pubmed-article:18348074lifeskim:mentionsumls-concept:C2603343lld:lifeskim
pubmed-article:18348074lifeskim:mentionsumls-concept:C1742737lld:lifeskim
pubmed-article:18348074lifeskim:mentionsumls-concept:C0101334lld:lifeskim
pubmed-article:18348074pubmed:issue1lld:pubmed
pubmed-article:18348074pubmed:dateCreated2008-3-18lld:pubmed
pubmed-article:18348074pubmed:abstractTextIn this study the influence of liposomal incorporation on both the stability and the in vitro (trans) dermal delivery of verbascoside was evaluated. The effect of drug entrapment into vesicles on its radical scavenging activity was also studied. Liposomes were obtained from soy phosphatidylcholine and cholesterol according to the film hydration method. Stability of verbascoside-loaded vesicles was studied over 6 months. Results showed that verbascoside can be incorporated in liposomes (E% = 57-66%), preventing its degradation. Stability studies (dynamic lager light scattering [DLLS] measurements and transmission electron microscopy [TEM] visualization) pointed out that vesicles were stable for 90 days and neither verbascoside leakage nor vesicle size alteration occurred during this period. The effects of vesicular incorporation on verbascoside diffusion through skin were investigated in vitro using newborn pig skin. Results showed that liposomes promoted drug accumulation into the stratum corneum but they did not give rise to any significant transdermal verbascoside delivery. Finally, results obtained from a 1, 1-diphenyl-2-pierylhydrazyl (DPPH) radical assay demonstrated that liposomes did not interfere with the radical scavenging activity of verbascoside.lld:pubmed
pubmed-article:18348074pubmed:languageenglld:pubmed
pubmed-article:18348074pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:18348074pubmed:citationSubsetIMlld:pubmed
pubmed-article:18348074pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:18348074pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:18348074pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:18348074pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:18348074pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:18348074pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:18348074pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:18348074pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:18348074pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:18348074pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:18348074pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:18348074pubmed:statusMEDLINElld:pubmed
pubmed-article:18348074pubmed:issn1532-2394lld:pubmed
pubmed-article:18348074pubmed:authorpubmed-author:ValentiDDlld:pubmed
pubmed-article:18348074pubmed:authorpubmed-author:VincieriF FFFlld:pubmed
pubmed-article:18348074pubmed:authorpubmed-author:FaddaA MAMlld:pubmed
pubmed-article:18348074pubmed:authorpubmed-author:BiliaA RARlld:pubmed
pubmed-article:18348074pubmed:authorpubmed-author:SinicoCClld:pubmed
pubmed-article:18348074pubmed:authorpubmed-author:CaddeoCClld:pubmed
pubmed-article:18348074pubmed:issnTypeElectroniclld:pubmed
pubmed-article:18348074pubmed:volume18lld:pubmed
pubmed-article:18348074pubmed:ownerNLMlld:pubmed
pubmed-article:18348074pubmed:authorsCompleteYlld:pubmed
pubmed-article:18348074pubmed:pagination83-90lld:pubmed
pubmed-article:18348074pubmed:dateRevised2009-11-19lld:pubmed
pubmed-article:18348074pubmed:meshHeadingpubmed-meshheading:18348074...lld:pubmed
pubmed-article:18348074pubmed:meshHeadingpubmed-meshheading:18348074...lld:pubmed
pubmed-article:18348074pubmed:meshHeadingpubmed-meshheading:18348074...lld:pubmed
pubmed-article:18348074pubmed:meshHeadingpubmed-meshheading:18348074...lld:pubmed
pubmed-article:18348074pubmed:meshHeadingpubmed-meshheading:18348074...lld:pubmed
pubmed-article:18348074pubmed:meshHeadingpubmed-meshheading:18348074...lld:pubmed
pubmed-article:18348074pubmed:meshHeadingpubmed-meshheading:18348074...lld:pubmed
pubmed-article:18348074pubmed:meshHeadingpubmed-meshheading:18348074...lld:pubmed
pubmed-article:18348074pubmed:meshHeadingpubmed-meshheading:18348074...lld:pubmed
pubmed-article:18348074pubmed:meshHeadingpubmed-meshheading:18348074...lld:pubmed
pubmed-article:18348074pubmed:meshHeadingpubmed-meshheading:18348074...lld:pubmed
pubmed-article:18348074pubmed:meshHeadingpubmed-meshheading:18348074...lld:pubmed
pubmed-article:18348074pubmed:meshHeadingpubmed-meshheading:18348074...lld:pubmed
pubmed-article:18348074pubmed:meshHeadingpubmed-meshheading:18348074...lld:pubmed
pubmed-article:18348074pubmed:meshHeadingpubmed-meshheading:18348074...lld:pubmed
pubmed-article:18348074pubmed:meshHeadingpubmed-meshheading:18348074...lld:pubmed
pubmed-article:18348074pubmed:meshHeadingpubmed-meshheading:18348074...lld:pubmed
pubmed-article:18348074pubmed:meshHeadingpubmed-meshheading:18348074...lld:pubmed
pubmed-article:18348074pubmed:year2008lld:pubmed
pubmed-article:18348074pubmed:articleTitleLiposomes as carriers for verbascoside: stability and skin permeation studies.lld:pubmed
pubmed-article:18348074pubmed:affiliationDipartimento Farmaco Chimico Tecnologico, Università di Cagliari, Cagliari, Italy. sinico@unica.itlld:pubmed
pubmed-article:18348074pubmed:publicationTypeJournal Articlelld:pubmed