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pubmed-article:18177048pubmed:abstractTextEfficiency in olefin cross-metathesis reactions is affected upon reducing the steric bulk of N-heterocyclic carbene ligands of ruthenium-based catalysts. For the formation of disubstituted olefins containing one or more allylic substituents, the catalyst bearing N-tolyl groups is more efficient than the corresponding N-mesityl catalyst. In contrast, the formation of trisubstituted olefins is more efficient using the N-mesityl-containing catalyst. A hypothesis to explain this dichotomy is described.lld:pubmed
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pubmed-article:18177048pubmed:articleTitleIncreased efficiency in cross-metathesis reactions of sterically hindered olefins.lld:pubmed
pubmed-article:18177048pubmed:affiliationThe Arnold and Mabel Beckman Laboratory of Chemical Synthesis, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.lld:pubmed
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