| pubmed-article:18070221 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18070221 | lifeskim:mentions | umls-concept:C0003289 | lld:lifeskim |
| pubmed-article:18070221 | lifeskim:mentions | umls-concept:C0178602 | lld:lifeskim |
| pubmed-article:18070221 | lifeskim:mentions | umls-concept:C0457454 | lld:lifeskim |
| pubmed-article:18070221 | lifeskim:mentions | umls-concept:C1707226 | lld:lifeskim |
| pubmed-article:18070221 | lifeskim:mentions | umls-concept:C1882417 | lld:lifeskim |
| pubmed-article:18070221 | lifeskim:mentions | umls-concept:C1444662 | lld:lifeskim |
| pubmed-article:18070221 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:18070221 | pubmed:dateCreated | 2008-3-12 | lld:pubmed |
| pubmed-article:18070221 | pubmed:abstractText | WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: * Most antidepressants are metabolized by CYP2D6. The variant allele CYP2D6*4 is the main polymorphism resulting in reduced enzyme activity in Caucasians. * Reduced enzyme activity potentially leads to increased toxicity of antidepressants, but the relevance of genotyping for clinical practice is unclear. Most clinical studies suffer from small numbers of patients. | lld:pubmed |
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| pubmed-article:18070221 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:18070221 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18070221 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:18070221 | pubmed:issn | 1365-2125 | lld:pubmed |
| pubmed-article:18070221 | pubmed:author | pubmed-author:HofmanAlbertA | lld:pubmed |
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| pubmed-article:18070221 | pubmed:author | pubmed-author:van... | lld:pubmed |
| pubmed-article:18070221 | pubmed:author | pubmed-author:VultoArnold... | lld:pubmed |
| pubmed-article:18070221 | pubmed:author | pubmed-author:van... | lld:pubmed |
| pubmed-article:18070221 | pubmed:author | pubmed-author:BijlMonique... | lld:pubmed |
| pubmed-article:18070221 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:18070221 | pubmed:volume | 65 | lld:pubmed |
| pubmed-article:18070221 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18070221 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18070221 | pubmed:pagination | 558-64 | lld:pubmed |
| pubmed-article:18070221 | pubmed:dateRevised | 2011-1-11 | lld:pubmed |
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| pubmed-article:18070221 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18070221 | pubmed:articleTitle | Influence of the CYP2D6*4 polymorphism on dose, switching and discontinuation of antidepressants. | lld:pubmed |
| pubmed-article:18070221 | pubmed:affiliation | Department of Epidemiology & Biostatistics, Erasmus MC, PO Box 2040, 3000 CA, Rotterdam, The Netherlands. | lld:pubmed |
| pubmed-article:18070221 | pubmed:publicationType | Journal Article | lld:pubmed |
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