| pubmed-article:17940768 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17940768 | lifeskim:mentions | umls-concept:C0040732 | lld:lifeskim |
| pubmed-article:17940768 | lifeskim:mentions | umls-concept:C0380603 | lld:lifeskim |
| pubmed-article:17940768 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:17940768 | lifeskim:mentions | umls-concept:C0476169 | lld:lifeskim |
| pubmed-article:17940768 | lifeskim:mentions | umls-concept:C0439859 | lld:lifeskim |
| pubmed-article:17940768 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:17940768 | pubmed:dateCreated | 2009-2-2 | lld:pubmed |
| pubmed-article:17940768 | pubmed:abstractText | In this study, we performed a mechanical analysis of the effect of fibroblast growth factor-2 (FGF-2) on autologous osteochondral transplantation in a rabbit model. A full-thickness cartilage defect (diameter: 5 mm; depth: 5 mm) made in the right femoral condyle was treated with osteochondral transplantation using an osteochondral plug (diameter: 6 mm; depth: 5 mm) taken from the left femoral condyle. The animals were divided into three groups: Group I, the defect was filled with 0.1 ml of gelatin hydrogel containing 1 microg of FGF-2; Group II, the defect was filled with 0.1 ml of gelatin hydrogel only; Group III, the defect was left untreated. Thereafter, osteochondral plugs were transplanted and the transplanted osteochondral grafts were evaluated mechanically and histologically at postoperative weeks 1, 3, 8 and 12. The structural property of the osteochondral graft was significantly greater in Group I than in Groups II and III at postoperative week 3. Histological analysis at 3 weeks revealed a tendency towards increased subchondral bone trabeculae in Group I compared with the other groups. Autologous osteochondral grafts transplanted with gelatin hydrogel containing FGF-2 acquired adequate stiffness at an early postoperative phase. | lld:pubmed |
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| pubmed-article:17940768 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17940768 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17940768 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17940768 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17940768 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17940768 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17940768 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:17940768 | pubmed:issn | 1432-5195 | lld:pubmed |
| pubmed-article:17940768 | pubmed:author | pubmed-author:TabataYasuhik... | lld:pubmed |
| pubmed-article:17940768 | pubmed:author | pubmed-author:KurosakaMasah... | lld:pubmed |
| pubmed-article:17940768 | pubmed:author | pubmed-author:KurodaRyosuke... | lld:pubmed |
| pubmed-article:17940768 | pubmed:author | pubmed-author:FujiokaHiroyu... | lld:pubmed |
| pubmed-article:17940768 | pubmed:author | pubmed-author:NakayamaJun-I... | lld:pubmed |
| pubmed-article:17940768 | pubmed:author | pubmed-author:MakinoTakeshi... | lld:pubmed |
| pubmed-article:17940768 | pubmed:author | pubmed-author:KokubuTakeshi... | lld:pubmed |
| pubmed-article:17940768 | pubmed:author | pubmed-author:NaguraIsseiI | lld:pubmed |
| pubmed-article:17940768 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:17940768 | pubmed:volume | 33 | lld:pubmed |
| pubmed-article:17940768 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17940768 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17940768 | pubmed:pagination | 275-80 | lld:pubmed |
| pubmed-article:17940768 | pubmed:dateRevised | 2010-9-15 | lld:pubmed |
| pubmed-article:17940768 | pubmed:meshHeading | pubmed-meshheading:17940768... | lld:pubmed |
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| pubmed-article:17940768 | pubmed:meshHeading | pubmed-meshheading:17940768... | lld:pubmed |
| pubmed-article:17940768 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:17940768 | pubmed:articleTitle | The effect of fibroblast growth factor-2 on autologous osteochondral transplantation. | lld:pubmed |
| pubmed-article:17940768 | pubmed:affiliation | Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan. | lld:pubmed |
| pubmed-article:17940768 | pubmed:publicationType | Journal Article | lld:pubmed |
