| pubmed-article:17936631 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17936631 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:17936631 | lifeskim:mentions | umls-concept:C0529196 | lld:lifeskim |
| pubmed-article:17936631 | lifeskim:mentions | umls-concept:C0220825 | lld:lifeskim |
| pubmed-article:17936631 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:17936631 | lifeskim:mentions | umls-concept:C0243077 | lld:lifeskim |
| pubmed-article:17936631 | lifeskim:mentions | umls-concept:C1707689 | lld:lifeskim |
| pubmed-article:17936631 | lifeskim:mentions | umls-concept:C0205460 | lld:lifeskim |
| pubmed-article:17936631 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:17936631 | pubmed:dateCreated | 2008-1-14 | lld:pubmed |
| pubmed-article:17936631 | pubmed:abstractText | A series of coumarin types MMP inhibitors were designed based on gelastatin hydroxamates (1) and evaluated for TACE, cellular TNF-alpha, and NO inhibitory activities. Among them, compounds 9b had potent inhibitory activities in enzymatic and cellular assays and good selectivity to MMP-2 and MMP-9. Further investigation of 9b will be carried out for its efficacy in RA animal model system. | lld:pubmed |
| pubmed-article:17936631 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17936631 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17936631 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17936631 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17936631 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17936631 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17936631 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17936631 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17936631 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17936631 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17936631 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17936631 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17936631 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17936631 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17936631 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:17936631 | pubmed:issn | 1464-3391 | lld:pubmed |
| pubmed-article:17936631 | pubmed:author | pubmed-author:ChoiYongseokY | lld:pubmed |
| pubmed-article:17936631 | pubmed:author | pubmed-author:KimHwan... | lld:pubmed |
| pubmed-article:17936631 | pubmed:author | pubmed-author:LeeHee-YoonHY | lld:pubmed |
| pubmed-article:17936631 | pubmed:author | pubmed-author:JoeBo-YoungBY | lld:pubmed |
| pubmed-article:17936631 | pubmed:author | pubmed-author:ParkChun-HoCH | lld:pubmed |
| pubmed-article:17936631 | pubmed:author | pubmed-author:HanGyoonheeG | lld:pubmed |
| pubmed-article:17936631 | pubmed:author | pubmed-author:KimMyung... | lld:pubmed |
| pubmed-article:17936631 | pubmed:author | pubmed-author:ParkSong-KyuS... | lld:pubmed |
| pubmed-article:17936631 | pubmed:author | pubmed-author:HongSung... | lld:pubmed |
| pubmed-article:17936631 | pubmed:author | pubmed-author:NamKy-YoubKY | lld:pubmed |
| pubmed-article:17936631 | pubmed:author | pubmed-author:KimMyung-HwaM... | lld:pubmed |
| pubmed-article:17936631 | pubmed:author | pubmed-author:ChoiHyun-MooH... | lld:pubmed |
| pubmed-article:17936631 | pubmed:author | pubmed-author:ChunKwangwooK | lld:pubmed |
| pubmed-article:17936631 | pubmed:author | pubmed-author:ChunTae GyuTG | lld:pubmed |
| pubmed-article:17936631 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:17936631 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:17936631 | pubmed:volume | 16 | lld:pubmed |
| pubmed-article:17936631 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17936631 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17936631 | pubmed:pagination | 530-5 | lld:pubmed |
| pubmed-article:17936631 | pubmed:meshHeading | pubmed-meshheading:17936631... | lld:pubmed |
| pubmed-article:17936631 | pubmed:meshHeading | pubmed-meshheading:17936631... | lld:pubmed |
| pubmed-article:17936631 | pubmed:meshHeading | pubmed-meshheading:17936631... | lld:pubmed |
| pubmed-article:17936631 | pubmed:meshHeading | pubmed-meshheading:17936631... | lld:pubmed |
| pubmed-article:17936631 | pubmed:meshHeading | pubmed-meshheading:17936631... | lld:pubmed |
| pubmed-article:17936631 | pubmed:meshHeading | pubmed-meshheading:17936631... | lld:pubmed |
| pubmed-article:17936631 | pubmed:meshHeading | pubmed-meshheading:17936631... | lld:pubmed |
| pubmed-article:17936631 | pubmed:meshHeading | pubmed-meshheading:17936631... | lld:pubmed |
| pubmed-article:17936631 | pubmed:meshHeading | pubmed-meshheading:17936631... | lld:pubmed |
| pubmed-article:17936631 | pubmed:meshHeading | pubmed-meshheading:17936631... | lld:pubmed |
| pubmed-article:17936631 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:17936631 | pubmed:articleTitle | Chromen-based TNF-alpha converting enzyme (TACE) inhibitors: design, synthesis, and biological evaluation. | lld:pubmed |
| pubmed-article:17936631 | pubmed:affiliation | Department of Biotechnology, Yonsei University, Seodaemun-gu, Seoul 120-740, Republic of Korea. | lld:pubmed |
| pubmed-article:17936631 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17936631 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:17936631 | lld:chembl |
