Volatile agents can mimic ischaemic preconditioning leading to a decrease in myocardial infarct size. The present study investigated if a 15 min sevoflurane administration before cardiopulmonary bypass (CPB) has a cardioprotective effect in patients undergoing coronary surgery.
Sevoflurane preconditioning at 1 MAC only provides limited protection in patients undergoing coronary artery bypass surgery: a randomized bi-centre trial.
EA 1896, Service d'Anesthésie Réanimation, Centre Hospitalier Lyon Sud, Université Claude Bernard Lyon 1, 69495 Pierre Bénite Cedex, France. piriou@univ-lyon1.fr
