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pubmed-article:17883871pubmed:abstractTextDrug resistance is a major problem in cancer chemotherapy. Acquisition of chemo-resistance not only reduces the effectiveness of drugs, but also promotes side effects and markedly reduces the patient's quality of life. However, a number of resistance mechanisms have been reported and are thought to be the reason for the difficulties in solving drug-resistance problems.lld:pubmed
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pubmed-article:17883871pubmed:articleTitleSwainsonine reduces 5-fluorouracil tolerance in the multistage resistance of colorectal cancer cell lines.lld:pubmed
pubmed-article:17883871pubmed:affiliationDepartment of General Surgery, Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan. hama@med.hokudai.ac.jplld:pubmed
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