| pubmed-article:17879090 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17879090 | lifeskim:mentions | umls-concept:C0011923 | lld:lifeskim |
| pubmed-article:17879090 | lifeskim:mentions | umls-concept:C0039225 | lld:lifeskim |
| pubmed-article:17879090 | lifeskim:mentions | umls-concept:C0037815 | lld:lifeskim |
| pubmed-article:17879090 | lifeskim:mentions | umls-concept:C1879886 | lld:lifeskim |
| pubmed-article:17879090 | lifeskim:mentions | umls-concept:C1706080 | lld:lifeskim |
| pubmed-article:17879090 | lifeskim:mentions | umls-concept:C0282183 | lld:lifeskim |
| pubmed-article:17879090 | lifeskim:mentions | umls-concept:C1553466 | lld:lifeskim |
| pubmed-article:17879090 | lifeskim:mentions | umls-concept:C0052432 | lld:lifeskim |
| pubmed-article:17879090 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:17879090 | lifeskim:mentions | umls-concept:C1711330 | lld:lifeskim |
| pubmed-article:17879090 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:17879090 | pubmed:dateCreated | 2007-10-30 | lld:pubmed |
| pubmed-article:17879090 | pubmed:abstractText | In support of the efforts to combat the illegal sale and distribution of counterfeit anti-malarial drugs, we evaluated a new analytical approach for the characterization and fast screening of fake and genuine artesunate tablets using a combination of Raman spectroscopy, Spatially Offset Raman Spectroscopy (SORS) and Attenuated Total Reflection-Fourier Transform Infrared (ATR-FTIR) imaging. Vibrational spectroscopy provided chemically specific information on the composition of the tablets; the complementary nature of Raman scattering and FTIR imaging allowed the characterization of both the overall and surface composition of the tablets. The depth-resolving power of the SORS approach provided chemically specific information on the overall composition of the tablets, non-invasively, through a variety of packaging types. Spatial imaging of the tablet surface (using ATR-FTIR) identified the location of domains of excipients and active ingredients with high sensitivity and enhanced spatial resolution. The advantages provided by a combination of SORS and ATR-FTIR imaging in this context confirm its potential for inclusion in the analytical protocol for forensic investigation of counterfeit medicines. | lld:pubmed |
| pubmed-article:17879090 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17879090 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17879090 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17879090 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17879090 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17879090 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17879090 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17879090 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17879090 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17879090 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17879090 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:17879090 | pubmed:issn | 1618-2642 | lld:pubmed |
| pubmed-article:17879090 | pubmed:author | pubmed-author:NewtonPaul... | lld:pubmed |
| pubmed-article:17879090 | pubmed:author | pubmed-author:MatousekPavel... | lld:pubmed |
| pubmed-article:17879090 | pubmed:author | pubmed-author:KazarianSerge... | lld:pubmed |
| pubmed-article:17879090 | pubmed:author | pubmed-author:EliassonCharl... | lld:pubmed |
| pubmed-article:17879090 | pubmed:author | pubmed-author:RicciCamillaC | lld:pubmed |
| pubmed-article:17879090 | pubmed:author | pubmed-author:MacleodNeil... | lld:pubmed |
| pubmed-article:17879090 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17879090 | pubmed:volume | 389 | lld:pubmed |
| pubmed-article:17879090 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17879090 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17879090 | pubmed:pagination | 1525-32 | lld:pubmed |
| pubmed-article:17879090 | pubmed:meshHeading | pubmed-meshheading:17879090... | lld:pubmed |
| pubmed-article:17879090 | pubmed:meshHeading | pubmed-meshheading:17879090... | lld:pubmed |
| pubmed-article:17879090 | pubmed:meshHeading | pubmed-meshheading:17879090... | lld:pubmed |
| pubmed-article:17879090 | pubmed:meshHeading | pubmed-meshheading:17879090... | lld:pubmed |
| pubmed-article:17879090 | pubmed:meshHeading | pubmed-meshheading:17879090... | lld:pubmed |
| pubmed-article:17879090 | pubmed:meshHeading | pubmed-meshheading:17879090... | lld:pubmed |
| pubmed-article:17879090 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17879090 | pubmed:articleTitle | Characterization of genuine and fake artesunate anti-malarial tablets using Fourier transform infrared imaging and spatially offset Raman spectroscopy through blister packs. | lld:pubmed |
| pubmed-article:17879090 | pubmed:affiliation | Department of Chemical Engineering, Imperial College London, London SW7 2AZ, UK. | lld:pubmed |
| pubmed-article:17879090 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17879090 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
