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pubmed-article:17873075pubmed:abstractTextDegradation of bis(2-chloroethyl) ether (BCEE) was observed to occur in two bacterial strains. Strain ENV481, a Xanthobacter sp. strain, was isolated by enrichment culturing of samples from a Superfund site located in the northeastern United States. The strain was able to grow on BCEE or 2-chloroethylethyl ether as the sole source of carbon and energy. BCEE degradation in strain ENV481 was facilitated by sequential dehalogenation reactions resulting in the formation of 2-(2-chloroethoxy)ethanol and diethylene glycol (DEG), respectively. 2-Hydroxyethoxyacetic acid was detected as a product of DEG catabolism by the strain. Degradation of BCEE by strain ENV481 was independent of oxygen, and the strain was not able to grow on a mixture of benzene, ethylbenzene, toluene, and xylenes, other prevalent contaminants at the site. Another bacterial isolate, Pseudonocardia sp. strain ENV478 (S. Vainberg et al., Appl. Environ. Microbiol. 72:5218-5224, 2006), degraded BCEE after growth on tetrahydrofuran or propane but was not able to grow on BCEE as a sole carbon source. BCEE degradation by strain ENV478 appeared to be facilitated by a monooxygenase-mediated O-dealkylation mechanism, and it resulted in the accumulation of 2-chloroacetic acid that was not readily degraded by the strain.lld:pubmed
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pubmed-article:17873075pubmed:dateRevised2010-9-15lld:pubmed
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pubmed-article:17873075pubmed:articleTitleBiodegradation of bis(2-chloroethyl) ether by Xanthobacter sp. strain ENV481.lld:pubmed
pubmed-article:17873075pubmed:affiliationShaw Environmental, Inc., Lawrenceville, NJ 08648, USA.lld:pubmed
pubmed-article:17873075pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:17873075pubmed:publicationTypeResearch Support, U.S. Gov't, Non-P.H.S.lld:pubmed