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pubmed-article:17786611pubmed:abstractTextThe adoptive transfer of ex vivo-induced tumor-specific T-cell lines provides a promising approach for cancer immunotherapy. We have demonstrated previously the feasibility of inducing in vitro long-term anti-tumor cytotoxic T-cell (CTL) lines directed against different types of solid tumors derived from both autologous and allogeneic PBMC. We have now investigated the possibility of producing large amounts of autologous anti-tumor CTL, in compliance with good manufacturing practices, for in vivo use.lld:pubmed
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pubmed-article:17786611pubmed:articleTitleGMP production of anti-tumor cytotoxic T-cell lines for adoptive T-cell therapy in patients with solid neoplasia.lld:pubmed
pubmed-article:17786611pubmed:affiliationImmunology Laboratory and Pediatric Hematology/Oncology, IRCCS Policlinico San Matteo, Milan, Italy.lld:pubmed
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