| pubmed-article:17766109 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17766109 | lifeskim:mentions | umls-concept:C0521009 | lld:lifeskim |
| pubmed-article:17766109 | lifeskim:mentions | umls-concept:C0040648 | lld:lifeskim |
| pubmed-article:17766109 | lifeskim:mentions | umls-concept:C0450442 | lld:lifeskim |
| pubmed-article:17766109 | lifeskim:mentions | umls-concept:C0243077 | lld:lifeskim |
| pubmed-article:17766109 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:17766109 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:17766109 | pubmed:issue | 20 | lld:pubmed |
| pubmed-article:17766109 | pubmed:dateCreated | 2007-9-18 | lld:pubmed |
| pubmed-article:17766109 | pubmed:abstractText | Structure-based drug design was utilized to identify potent small-molecule inhibitors of proteins within the AraC family of bacterial transcription factors, which control virulence in medically important microbes. These agents represent a novel approach to fight infectious disease and may be less likely to promote resistance development. These compounds lack intrinsic antibacterial activity in vitro and were able to limit a bacterial infection in a mouse model of urinary tract infection. | lld:pubmed |
| pubmed-article:17766109 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17766109 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17766109 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:17766109 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17766109 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:17766109 | pubmed:issn | 0960-894X | lld:pubmed |
| pubmed-article:17766109 | pubmed:author | pubmed-author:LevyStuart... | lld:pubmed |
| pubmed-article:17766109 | pubmed:author | pubmed-author:GrierMark CMC | lld:pubmed |
| pubmed-article:17766109 | pubmed:author | pubmed-author:VermaAtul KAK | lld:pubmed |
| pubmed-article:17766109 | pubmed:author | pubmed-author:AlekshunMicha... | lld:pubmed |
| pubmed-article:17766109 | pubmed:author | pubmed-author:BowserTodd... | lld:pubmed |
| pubmed-article:17766109 | pubmed:author | pubmed-author:BartlettVicto... | lld:pubmed |
| pubmed-article:17766109 | pubmed:author | pubmed-author:WarcholTadues... | lld:pubmed |
| pubmed-article:17766109 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17766109 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:17766109 | pubmed:volume | 17 | lld:pubmed |
| pubmed-article:17766109 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17766109 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17766109 | pubmed:pagination | 5652-5 | lld:pubmed |
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| pubmed-article:17766109 | pubmed:meshHeading | pubmed-meshheading:17766109... | lld:pubmed |
| pubmed-article:17766109 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17766109 | pubmed:articleTitle | Novel anti-infection agents: small-molecule inhibitors of bacterial transcription factors. | lld:pubmed |
| pubmed-article:17766109 | pubmed:affiliation | Paratek Pharmaceuticals, Inc., 75 Kneeland Street, Boston, MA 02111, USA. tbowser@paratekpharm.com | lld:pubmed |
| pubmed-article:17766109 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:17766109 | lld:chembl |
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