| pubmed-article:17690132 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17690132 | lifeskim:mentions | umls-concept:C0011253 | lld:lifeskim |
| pubmed-article:17690132 | lifeskim:mentions | umls-concept:C0033975 | lld:lifeskim |
| pubmed-article:17690132 | lifeskim:mentions | umls-concept:C1710082 | lld:lifeskim |
| pubmed-article:17690132 | lifeskim:mentions | umls-concept:C1551359 | lld:lifeskim |
| pubmed-article:17690132 | lifeskim:mentions | umls-concept:C0332120 | lld:lifeskim |
| pubmed-article:17690132 | pubmed:issue | Pt 9 | lld:pubmed |
| pubmed-article:17690132 | pubmed:dateCreated | 2007-8-22 | lld:pubmed |
| pubmed-article:17690132 | pubmed:abstractText | Delusions are maladaptive beliefs about the world. Based upon experimental evidence that prediction error-a mismatch between expectancy and outcome--drives belief formation, this study examined the possibility that delusions form because of disrupted prediction--error processing. We used fMRI to determine prediction-error-related brain responses in 12 healthy subjects and 12 individuals (7 males) with delusional beliefs. Frontal cortex responses in the patient group were suggestive of disrupted prediction-error processing. Furthermore, across subjects, the extent of disruption was significantly related to an individual's propensity to delusion formation. Our results support a neurobiological theory of delusion formation that implicates aberrant prediction-error signalling, disrupted attentional allocation and associative learning in the formation of delusional beliefs. | lld:pubmed |
| pubmed-article:17690132 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:17690132 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17690132 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17690132 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:17690132 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17690132 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17690132 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:17690132 | pubmed:issn | 1460-2156 | lld:pubmed |
| pubmed-article:17690132 | pubmed:author | pubmed-author:RobbinsT WTW | lld:pubmed |
| pubmed-article:17690132 | pubmed:author | pubmed-author:DickinsonAA | lld:pubmed |
| pubmed-article:17690132 | pubmed:author | pubmed-author:MurrayG KGK | lld:pubmed |
| pubmed-article:17690132 | pubmed:author | pubmed-author:ShanksD RDR | lld:pubmed |
| pubmed-article:17690132 | pubmed:author | pubmed-author:FletcherP CPC | lld:pubmed |
| pubmed-article:17690132 | pubmed:author | pubmed-author:BullmoreE TET | lld:pubmed |
| pubmed-article:17690132 | pubmed:author | pubmed-author:HoneyG DGD | lld:pubmed |
| pubmed-article:17690132 | pubmed:author | pubmed-author:AitkenM R FMR | lld:pubmed |
| pubmed-article:17690132 | pubmed:author | pubmed-author:CorlettP RPR | lld:pubmed |
| pubmed-article:17690132 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:17690132 | pubmed:volume | 130 | lld:pubmed |
| pubmed-article:17690132 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17690132 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17690132 | pubmed:pagination | 2387-400 | lld:pubmed |
| pubmed-article:17690132 | pubmed:dateRevised | 2010-4-30 | lld:pubmed |
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| pubmed-article:17690132 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17690132 | pubmed:articleTitle | Disrupted prediction-error signal in psychosis: evidence for an associative account of delusions. | lld:pubmed |
| pubmed-article:17690132 | pubmed:affiliation | Brain Mapping Unit, Department of Psychiatry, University of Cambridge, School of Clinical Medicine, Addenbrooke's Hospital, Cambridge CB2 2QQ, UK. | lld:pubmed |
| pubmed-article:17690132 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17690132 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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