| pubmed-article:17509569 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17509569 | lifeskim:mentions | umls-concept:C0521449 | lld:lifeskim |
| pubmed-article:17509569 | lifeskim:mentions | umls-concept:C1956015 | lld:lifeskim |
| pubmed-article:17509569 | lifeskim:mentions | umls-concept:C1254042 | lld:lifeskim |
| pubmed-article:17509569 | lifeskim:mentions | umls-concept:C0887840 | lld:lifeskim |
| pubmed-article:17509569 | pubmed:issue | 15 | lld:pubmed |
| pubmed-article:17509569 | pubmed:dateCreated | 2007-6-11 | lld:pubmed |
| pubmed-article:17509569 | pubmed:abstractText | Based on the characterization of ribosome precursor particles and associated trans-acting factors, a biogenesis pathway for the 40S and 60S subunits has emerged. After nuclear synthesis and assembly steps, pre-ribosomal subunits are exported through the nuclear pore complex in a Crm1- and RanGTP-dependent manner. Subsequent cytoplasmic biogenesis steps of pre-60S particles include the facilitated release of several non-ribosomal proteins, yielding fully functional 60S subunits. Cytoplasmic maturation of 40S subunit precursors includes rRNA dimethylation and pre-rRNA cleavage, allowing 40S subunits to achieve translation competence. We review current knowledge of nuclear export and cytoplasmic maturation of ribosomal subunits. | lld:pubmed |
| pubmed-article:17509569 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17509569 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17509569 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:17509569 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17509569 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:17509569 | pubmed:issn | 0014-5793 | lld:pubmed |
| pubmed-article:17509569 | pubmed:author | pubmed-author:KutayUlrikeU | lld:pubmed |
| pubmed-article:17509569 | pubmed:author | pubmed-author:ZempIvoI | lld:pubmed |
| pubmed-article:17509569 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17509569 | pubmed:day | 19 | lld:pubmed |
| pubmed-article:17509569 | pubmed:volume | 581 | lld:pubmed |
| pubmed-article:17509569 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17509569 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17509569 | pubmed:pagination | 2783-93 | lld:pubmed |
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| pubmed-article:17509569 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17509569 | pubmed:articleTitle | Nuclear export and cytoplasmic maturation of ribosomal subunits. | lld:pubmed |
| pubmed-article:17509569 | pubmed:affiliation | Institute of Biochemistry, HPM F11.1, Schafmattstr. 18, ETH Zurich, 8093 Zurich, Switzerland. | lld:pubmed |
| pubmed-article:17509569 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17509569 | pubmed:publicationType | Review | lld:pubmed |
| pubmed-article:17509569 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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