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pubmed-article:17473340pubmed:dateCreated2007-5-2lld:pubmed
pubmed-article:17473340pubmed:abstractTextPolymer gel dosimetry aims to provide three-dimensional images of radiation therapy dose distributions in irradiated aqueous gels. The first gels required manufacture in an oxygen-free environment, but later the MAGIC formulation was introduced, which could be made in normal atmospheric conditions. Here we report our studies of the effects of variations in the composition of the MAGIC gel performed in order to optimize its performance over the useful dose range of 0 to 20 Gy. A new formulation (termed 'MAGIC-2') is comprised of 87% water, 4% methacrylic acid, 9% gelatin, 17.38 x 10(-6) M Cu(2+) and a molar ratio of ascorbic acid to [Cu(2+)] of 1000:1. MAGIC-2 has a dose-response slope-to-intercept ratio that is 78% greater than the original formulation and other more favorable properties.lld:pubmed
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pubmed-article:17473340pubmed:authorpubmed-author:GoreJ CJClld:pubmed
pubmed-article:17473340pubmed:authorpubmed-author:WhitneyH MHMlld:pubmed
pubmed-article:17473340pubmed:authorpubmed-author:LuciJ JJJlld:pubmed
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pubmed-article:17473340pubmed:paginationN241-8lld:pubmed
pubmed-article:17473340pubmed:dateRevised2007-12-3lld:pubmed
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pubmed-article:17473340pubmed:year2007lld:pubmed
pubmed-article:17473340pubmed:articleTitleOptimization of MAGIC gel formulation for three-dimensional radiation therapy dosimetry.lld:pubmed
pubmed-article:17473340pubmed:affiliationVanderbilt University Institute of Imaging Science, Nashville, TN 37232-2675, USA.lld:pubmed
pubmed-article:17473340pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:17473340pubmed:publicationTypeResearch Support, N.I.H., Extramurallld:pubmed
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