| pubmed-article:17467062 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17467062 | lifeskim:mentions | umls-concept:C1457887 | lld:lifeskim |
| pubmed-article:17467062 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
| pubmed-article:17467062 | lifeskim:mentions | umls-concept:C0014072 | lld:lifeskim |
| pubmed-article:17467062 | lifeskim:mentions | umls-concept:C0205191 | lld:lifeskim |
| pubmed-article:17467062 | lifeskim:mentions | umls-concept:C0332162 | lld:lifeskim |
| pubmed-article:17467062 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:17467062 | pubmed:dateCreated | 2007-5-28 | lld:pubmed |
| pubmed-article:17467062 | pubmed:abstractText | The homophilic cell adhesion molecule PECAM-1 is a major participant in the migration of leukocytes across endothelium. We examined the ability of a chimeric soluble PECAM-1 fused to human IgG-Fc to impair leukocyte entry through the blood-brain barrier and reduce CNS autoimmunity. sPECAM-Fc impaired migration of lymphocytes across brain endothelial monolayers and diminished the severity of EAE, an experimental model of MS, when administered at the onset of symptoms. However, in mice transgenic for sPECAM-Fc, the chronically elevated levels of sPECAM-Fc hastened onset of EAE disease without significantly changing clinical score severity. Our data suggest that short-term treatment of diseases like MS with sPECAM-Fc has therapeutic potential. | lld:pubmed |
| pubmed-article:17467062 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17467062 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17467062 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17467062 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17467062 | pubmed:month | May | lld:pubmed |
| pubmed-article:17467062 | pubmed:issn | 0165-5728 | lld:pubmed |
| pubmed-article:17467062 | pubmed:author | pubmed-author:MullerWilliam... | lld:pubmed |
| pubmed-article:17467062 | pubmed:author | pubmed-author:SandorMatyasM | lld:pubmed |
| pubmed-article:17467062 | pubmed:author | pubmed-author:ReinkeEmily... | lld:pubmed |
| pubmed-article:17467062 | pubmed:author | pubmed-author:KarmanJozsefJ | lld:pubmed |
| pubmed-article:17467062 | pubmed:author | pubmed-author:FabryZsuzsann... | lld:pubmed |
| pubmed-article:17467062 | pubmed:author | pubmed-author:ZozulyaAllaA | lld:pubmed |
| pubmed-article:17467062 | pubmed:author | pubmed-author:LeeJangeunJ | lld:pubmed |
| pubmed-article:17467062 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17467062 | pubmed:volume | 186 | lld:pubmed |
| pubmed-article:17467062 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17467062 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17467062 | pubmed:pagination | 86-93 | lld:pubmed |
| pubmed-article:17467062 | pubmed:dateRevised | 2011-3-25 | lld:pubmed |
| pubmed-article:17467062 | pubmed:meshHeading | pubmed-meshheading:17467062... | lld:pubmed |
| pubmed-article:17467062 | pubmed:meshHeading | pubmed-meshheading:17467062... | lld:pubmed |
| pubmed-article:17467062 | pubmed:meshHeading | pubmed-meshheading:17467062... | lld:pubmed |
| pubmed-article:17467062 | pubmed:meshHeading | pubmed-meshheading:17467062... | lld:pubmed |
| pubmed-article:17467062 | pubmed:meshHeading | pubmed-meshheading:17467062... | lld:pubmed |
| pubmed-article:17467062 | pubmed:meshHeading | pubmed-meshheading:17467062... | lld:pubmed |
| pubmed-article:17467062 | pubmed:meshHeading | pubmed-meshheading:17467062... | lld:pubmed |
| pubmed-article:17467062 | pubmed:meshHeading | pubmed-meshheading:17467062... | lld:pubmed |
| pubmed-article:17467062 | pubmed:meshHeading | pubmed-meshheading:17467062... | lld:pubmed |
| pubmed-article:17467062 | pubmed:meshHeading | pubmed-meshheading:17467062... | lld:pubmed |
| pubmed-article:17467062 | pubmed:meshHeading | pubmed-meshheading:17467062... | lld:pubmed |
| pubmed-article:17467062 | pubmed:meshHeading | pubmed-meshheading:17467062... | lld:pubmed |
| pubmed-article:17467062 | pubmed:meshHeading | pubmed-meshheading:17467062... | lld:pubmed |
| pubmed-article:17467062 | pubmed:meshHeading | pubmed-meshheading:17467062... | lld:pubmed |
| pubmed-article:17467062 | pubmed:meshHeading | pubmed-meshheading:17467062... | lld:pubmed |
| pubmed-article:17467062 | pubmed:meshHeading | pubmed-meshheading:17467062... | lld:pubmed |
| pubmed-article:17467062 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17467062 | pubmed:articleTitle | Short-term sPECAM-Fc treatment ameliorates EAE while chronic use hastens onset of symptoms. | lld:pubmed |
| pubmed-article:17467062 | pubmed:affiliation | Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA. | lld:pubmed |
| pubmed-article:17467062 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17467062 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:17467062 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| entrez-gene:18613 | entrezgene:pubmed | pubmed-article:17467062 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:17467062 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:17467062 | lld:pubmed |
