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pubmed-article:17452775pubmed:abstractTextHypoxia modifies the phenotype of tumors in a way that promotes tumor aggressiveness and resistance towards chemotherapy and radiotherapy. However, the expression and influence of hypoxia-regulated proteins on tumor biology are not well characterized in colorectal tumors. We studied the role of protein expression of hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, carbonic anhydrase 9 (CA9) and glucose transporter 1 (GLUT1) in patients with colorectal adenocarcinomas.lld:pubmed
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pubmed-article:17452775pubmed:articleTitleStromal expression of hypoxia regulated proteins is an adverse prognostic factor in colorectal carcinomas.lld:pubmed
pubmed-article:17452775pubmed:affiliationDepartments of Pathology, GROW Research Institute, University Hospital Maastricht, PO Box 5800, 6202 AZ Maastricht, The Netherlands.lld:pubmed
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