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pubmed-article:17343744pubmed:abstractTextComplete genome sequences of the Astroviridae include human, non-human mammalian and avian species. A consensus topology of astroviruses has been derived from nucleotide substitutions in the full-length genomes and from non-synonymous nucleotide substitutions in each of the three ORFs. Analyses of synonymous substitutions displayed a loss of tree structure, suggesting either saturation of the substitution model or a deviant pattern of synonymous substitutions in certain virus species.lld:pubmed
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pubmed-article:17343744pubmed:articleTitleDifferent rates of (non-)synonymous mutations in astrovirus genes; correlation with gene function.lld:pubmed
pubmed-article:17343744pubmed:affiliationLaboratory of Experimental Virology, Department of Medical Microbiology, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, University of Amsterdam, The Netherlands. f.j.vanhemert@amc.uva.nllld:pubmed
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