| pubmed-article:17308846 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17308846 | lifeskim:mentions | umls-concept:C0006434 | lld:lifeskim |
| pubmed-article:17308846 | lifeskim:mentions | umls-concept:C0043250 | lld:lifeskim |
| pubmed-article:17308846 | lifeskim:mentions | umls-concept:C0028128 | lld:lifeskim |
| pubmed-article:17308846 | lifeskim:mentions | umls-concept:C2004454 | lld:lifeskim |
| pubmed-article:17308846 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:17308846 | pubmed:dateCreated | 2007-3-27 | lld:pubmed |
| pubmed-article:17308846 | pubmed:abstractText | A full-thickness burn wound model was used to evaluate the effects of a topically applied gel-based nitric oxide donor on wound healing in rats. The histological study demonstrated that the nitric oxide (NO) application significantly promoted re-epithelization that resulted in a fast recovery of burn wound. The histological sections further revealed that inflammatory cell infiltration in the NO-treated group was significantly increased in comparison to the control group. The enhanced accumulation of inflammatory cells resulted in a higher expression of myeloperoxidase (MPO) that was detected with imunoblotting. An immunohistochemistry study with CD31, a specific marker for endothelial cells, indicated that NO treatment markedly stimulated angiogenesis. Evaluation of collagen synthesis by immunohistochemistry with procollagen antibody demonstrated a significantly increased collagen synthesis in NO-treated wound bed. We concluded that NO treatment promoted re-epithelialization and wound closure by means of enhanced inflammatory cell infiltration, and that it promoted angiogenesis and facilitated collagen synthesis in the wound bed. | lld:pubmed |
| pubmed-article:17308846 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:17308846 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17308846 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17308846 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17308846 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17308846 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17308846 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:17308846 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17308846 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17308846 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:17308846 | pubmed:issn | 0364-2313 | lld:pubmed |
| pubmed-article:17308846 | pubmed:author | pubmed-author:ZhuHaifengH | lld:pubmed |
| pubmed-article:17308846 | pubmed:author | pubmed-author:MuradFeridF | lld:pubmed |
| pubmed-article:17308846 | pubmed:author | pubmed-author:BianKaK | lld:pubmed |
| pubmed-article:17308846 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17308846 | pubmed:volume | 31 | lld:pubmed |
| pubmed-article:17308846 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17308846 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17308846 | pubmed:pagination | 624-31 | lld:pubmed |
| pubmed-article:17308846 | pubmed:dateRevised | 2007-12-3 | lld:pubmed |
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| pubmed-article:17308846 | pubmed:meshHeading | pubmed-meshheading:17308846... | lld:pubmed |
| pubmed-article:17308846 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17308846 | pubmed:articleTitle | Nitric oxide accelerates the recovery from burn wounds. | lld:pubmed |
| pubmed-article:17308846 | pubmed:affiliation | Department of Integrative Biology and Pharmacology, Institute of Molecular Medicine, The University of Texas-Health Science Center at Houston, 6431 Fannin St, Houston, Texas 77030, USA. | lld:pubmed |
| pubmed-article:17308846 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17308846 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:17308846 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:17308846 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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