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pubmed-article:17288589pubmed:abstractTextThe timing of the origin of introns is of crucial importance for an understanding of early genome architecture. The Exon theory of genes proposed a role for introns in the formation of multi-exon proteins by exon shuffling and predicts the presence of conserved splice sites in ancient genes. In this study, large-scale analysis of potential conserved splice sites was performed using an intron-exon database (ExInt) derived from GenBank.lld:pubmed
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pubmed-article:17288589pubmed:dateRevised2009-11-18lld:pubmed
pubmed-article:17288589pubmed:year2007lld:pubmed
pubmed-article:17288589pubmed:articleTitleConserved intron positions in ancient protein modules.lld:pubmed
pubmed-article:17288589pubmed:affiliationSyncyte BioIntelligence, P.O. Box 600, 1000 AP, Amsterdam, The Netherlands. albert.de.roos@syncyte.comlld:pubmed
pubmed-article:17288589pubmed:publicationTypeJournal Articlelld:pubmed
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