| pubmed-article:1717736 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1717736 | lifeskim:mentions | umls-concept:C0012177 | lld:lifeskim |
| pubmed-article:1717736 | lifeskim:mentions | umls-concept:C0229671 | lld:lifeskim |
| pubmed-article:1717736 | lifeskim:mentions | umls-concept:C0022663 | lld:lifeskim |
| pubmed-article:1717736 | lifeskim:mentions | umls-concept:C0027697 | lld:lifeskim |
| pubmed-article:1717736 | lifeskim:mentions | umls-concept:C0443288 | lld:lifeskim |
| pubmed-article:1717736 | lifeskim:mentions | umls-concept:C1514118 | lld:lifeskim |
| pubmed-article:1717736 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:1717736 | pubmed:dateCreated | 1991-11-1 | lld:pubmed |
| pubmed-article:1717736 | pubmed:abstractText | We have previously demonstrated that long-term dietary protein restriction ameliorates proteinuria and limits glomerular structural injury in rats with nephrotoxic serum nephritis. In the present study, we examined the influence of short-term dietary protein restriction on glomerular permselectivity. As compared to nephritic rats maintained on a normal protein diet, whole kidney and single nephron hemodynamics were lower in nephritic rats subjected to dietary protein restriction of three days duration (glomerular filtration rate: 0.79 +/- 0.10 vs. 1.46 +/- 0.11 ml/min, P less than 0.003; renal plasma flow rate: 2.50 +/- 0.34 vs. 3.96 +/- 0.38 ml/min, P less than 0.02; glomerular capillary pressure: 44 +/- 1 vs. 53 +/- 1 mm Hg, P less than 0.002; proteinuria: 77 +/- 15 vs. 224 +/- 14 mg/24 hr, P less than 0.01). This was associated with a rise in afferent resistance, from 2.99 +/- 0.77 to 5.45 +/- 0.94 dyn.sec.cm-5, NS. In nephritic rats maintained on 24% protein, fractional clearances were elevated above control values for neutral dextrans with molecular radii exceeding 50 A but were depressed for those with molecular radii below 30 A (P less than 0.05). Dietary protein restriction elevated the fractional clearances of dextrans with radii less than 30 A while depressing the fractional clearances of dextrans with radii greater than 50 A (P less than 0.05). The proportion of glomerular filtrate permeating the shunt pathway was elevated above control values in nephritic rats on the 24% protein diet but declined in those fed the low protein diet (NSN-24%: 0.86%; NSN-6%: 0.31%; control: 0.19%).(ABSTRACT TRUNCATED AT 250 WORDS) | lld:pubmed |
| pubmed-article:1717736 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1717736 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1717736 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1717736 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1717736 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1717736 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1717736 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:1717736 | pubmed:issn | 0085-2538 | lld:pubmed |
| pubmed-article:1717736 | pubmed:author | pubmed-author:BaldwinD SDS | lld:pubmed |
| pubmed-article:1717736 | pubmed:author | pubmed-author:SchachtR GRG | lld:pubmed |
| pubmed-article:1717736 | pubmed:author | pubmed-author:KozinAA | lld:pubmed |
| pubmed-article:1717736 | pubmed:author | pubmed-author:NeugartenJJ | lld:pubmed |
| pubmed-article:1717736 | pubmed:author | pubmed-author:GaynerRR | lld:pubmed |
| pubmed-article:1717736 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1717736 | pubmed:volume | 40 | lld:pubmed |
| pubmed-article:1717736 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1717736 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1717736 | pubmed:pagination | 57-61 | lld:pubmed |
| pubmed-article:1717736 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:1717736 | pubmed:meshHeading | pubmed-meshheading:1717736-... | lld:pubmed |
| pubmed-article:1717736 | pubmed:meshHeading | pubmed-meshheading:1717736-... | lld:pubmed |
| pubmed-article:1717736 | pubmed:meshHeading | pubmed-meshheading:1717736-... | lld:pubmed |
| pubmed-article:1717736 | pubmed:meshHeading | pubmed-meshheading:1717736-... | lld:pubmed |
| pubmed-article:1717736 | pubmed:meshHeading | pubmed-meshheading:1717736-... | lld:pubmed |
| pubmed-article:1717736 | pubmed:meshHeading | pubmed-meshheading:1717736-... | lld:pubmed |
| pubmed-article:1717736 | pubmed:meshHeading | pubmed-meshheading:1717736-... | lld:pubmed |
| pubmed-article:1717736 | pubmed:meshHeading | pubmed-meshheading:1717736-... | lld:pubmed |
| pubmed-article:1717736 | pubmed:meshHeading | pubmed-meshheading:1717736-... | lld:pubmed |
| pubmed-article:1717736 | pubmed:meshHeading | pubmed-meshheading:1717736-... | lld:pubmed |
| pubmed-article:1717736 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1717736 | pubmed:articleTitle | Dietary protein restriction and glomerular permselectivity in nephrotoxic serum nephritis. | lld:pubmed |
| pubmed-article:1717736 | pubmed:affiliation | Hypertension and Renal Disease Section, Montefiore Medical Center, New York. | lld:pubmed |
| pubmed-article:1717736 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1717736 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1717736 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1717736 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1717736 | lld:pubmed |
