| pubmed-article:17069247 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17069247 | lifeskim:mentions | umls-concept:C0012984 | lld:lifeskim |
| pubmed-article:17069247 | lifeskim:mentions | umls-concept:C0032105 | lld:lifeskim |
| pubmed-article:17069247 | lifeskim:mentions | umls-concept:C0302908 | lld:lifeskim |
| pubmed-article:17069247 | lifeskim:mentions | umls-concept:C0003596 | lld:lifeskim |
| pubmed-article:17069247 | lifeskim:mentions | umls-concept:C0680730 | lld:lifeskim |
| pubmed-article:17069247 | lifeskim:mentions | umls-concept:C0037813 | lld:lifeskim |
| pubmed-article:17069247 | lifeskim:mentions | umls-concept:C0596801 | lld:lifeskim |
| pubmed-article:17069247 | lifeskim:mentions | umls-concept:C0185125 | lld:lifeskim |
| pubmed-article:17069247 | lifeskim:mentions | umls-concept:C0201734 | lld:lifeskim |
| pubmed-article:17069247 | lifeskim:mentions | umls-concept:C1148554 | lld:lifeskim |
| pubmed-article:17069247 | pubmed:issue | 14 | lld:pubmed |
| pubmed-article:17069247 | pubmed:dateCreated | 2006-10-30 | lld:pubmed |
| pubmed-article:17069247 | pubmed:abstractText | An LC-ESI-MS method was developed and validated for the assay of apomorphine in canine plasma using one-step liquid-liquid extraction. The analytes were separated on a Phenomenex Gemini C18 (150 mm x 2.0 mm id 3 microm) column and determined by MS in the positive ion mode. The linear range was 0.4-40 ng/mL with an LOD of 0.2 ng/mL for apomorphine in plasma. The intraday and interday precision and accuracy of quality control samples were < 5.9% RSD and < 7.5% bias for apomorphine. Extraction recoveries were > 80%. The validated method was successfully applied to analyze canine plasma samples in a pharmacokinetic study of apomorphine in dogs and detailed pharmacokinetic parameters were calculated. | lld:pubmed |
| pubmed-article:17069247 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17069247 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17069247 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17069247 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17069247 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17069247 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:17069247 | pubmed:issn | 1615-9306 | lld:pubmed |
| pubmed-article:17069247 | pubmed:author | pubmed-author:DaiM JMJ | lld:pubmed |
| pubmed-article:17069247 | pubmed:author | pubmed-author:DengChunhuiC | lld:pubmed |
| pubmed-article:17069247 | pubmed:author | pubmed-author:YangBeiB | lld:pubmed |
| pubmed-article:17069247 | pubmed:author | pubmed-author:DuanGengliG | lld:pubmed |
| pubmed-article:17069247 | pubmed:author | pubmed-author:YuYunqiuY | lld:pubmed |
| pubmed-article:17069247 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17069247 | pubmed:volume | 29 | lld:pubmed |
| pubmed-article:17069247 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17069247 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17069247 | pubmed:pagination | 2173-8 | lld:pubmed |
| pubmed-article:17069247 | pubmed:meshHeading | pubmed-meshheading:17069247... | lld:pubmed |
| pubmed-article:17069247 | pubmed:meshHeading | pubmed-meshheading:17069247... | lld:pubmed |
| pubmed-article:17069247 | pubmed:meshHeading | pubmed-meshheading:17069247... | lld:pubmed |
| pubmed-article:17069247 | pubmed:meshHeading | pubmed-meshheading:17069247... | lld:pubmed |
| pubmed-article:17069247 | pubmed:meshHeading | pubmed-meshheading:17069247... | lld:pubmed |
| pubmed-article:17069247 | pubmed:meshHeading | pubmed-meshheading:17069247... | lld:pubmed |
| pubmed-article:17069247 | pubmed:meshHeading | pubmed-meshheading:17069247... | lld:pubmed |
| pubmed-article:17069247 | pubmed:meshHeading | pubmed-meshheading:17069247... | lld:pubmed |
| pubmed-article:17069247 | pubmed:meshHeading | pubmed-meshheading:17069247... | lld:pubmed |
| pubmed-article:17069247 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:17069247 | pubmed:articleTitle | Determination of apomorphine in canine plasma by liquid chromatography-electrospray ionization mass spectrometry and its application to a pharmacokinetic study. | lld:pubmed |
| pubmed-article:17069247 | pubmed:affiliation | Department of Pharmaceutical Analysis, School of Pharmacy, Fudan University, Shanghai, PR China. | lld:pubmed |
| pubmed-article:17069247 | pubmed:publicationType | Journal Article | lld:pubmed |
