| pubmed-article:1705666 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1705666 | lifeskim:mentions | umls-concept:C0115305 | lld:lifeskim |
| pubmed-article:1705666 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
| pubmed-article:1705666 | lifeskim:mentions | umls-concept:C0007578 | lld:lifeskim |
| pubmed-article:1705666 | pubmed:issue | 6312 | lld:pubmed |
| pubmed-article:1705666 | pubmed:dateCreated | 1991-4-9 | lld:pubmed |
| pubmed-article:1705666 | pubmed:abstractText | Endothelial cell leukocyte adhesion molecule-1 (ELAM-1) has been described as an inducible endothelial cell-adhesion molecule for neutrophils, and is believed to have a key role in the extravasation of these cells at sites of acute inflammation. Here we report that ELAM-1-transfected COS cells also bind a unique skin-associated subset of circulating memory T cells defined by the expression of the cutaneous lymphocyte-associated antigen. T cells expressing this antigen bind at least as well as neutrophils to expressed ELAM-1, whereas other lymphocytes in the peripheral blood bind poorly, or not at all. Immunohistological survey of chronically inflamed tissue specimens revealed that vascular expression of ELAM-1 occurs at cutaneous sites in preference to noncutaneous sites. We conclude that at sites of chronic inflammation, ELAM-1 may function as a skin vascular addressin, a tissue-selective endothelial cell-adhesion molecule for skin-homing memory T lymphocytes. | lld:pubmed |
| pubmed-article:1705666 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1705666 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1705666 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1705666 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1705666 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1705666 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1705666 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1705666 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:1705666 | pubmed:issn | 0028-0836 | lld:pubmed |
| pubmed-article:1705666 | pubmed:author | pubmed-author:ButcherE CEC | lld:pubmed |
| pubmed-article:1705666 | pubmed:author | pubmed-author:SmithC WCW | lld:pubmed |
| pubmed-article:1705666 | pubmed:author | pubmed-author:KishimotoT... | lld:pubmed |
| pubmed-article:1705666 | pubmed:author | pubmed-author:PickerL JLJ | lld:pubmed |
| pubmed-article:1705666 | pubmed:author | pubmed-author:WarnockR ARA | lld:pubmed |
| pubmed-article:1705666 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1705666 | pubmed:day | 28 | lld:pubmed |
| pubmed-article:1705666 | pubmed:volume | 349 | lld:pubmed |
| pubmed-article:1705666 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1705666 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1705666 | pubmed:pagination | 796-9 | lld:pubmed |
| pubmed-article:1705666 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:1705666 | pubmed:meshHeading | pubmed-meshheading:1705666-... | lld:pubmed |
| pubmed-article:1705666 | pubmed:meshHeading | pubmed-meshheading:1705666-... | lld:pubmed |
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| pubmed-article:1705666 | pubmed:meshHeading | pubmed-meshheading:1705666-... | lld:pubmed |
| pubmed-article:1705666 | pubmed:meshHeading | pubmed-meshheading:1705666-... | lld:pubmed |
| pubmed-article:1705666 | pubmed:meshHeading | pubmed-meshheading:1705666-... | lld:pubmed |
| pubmed-article:1705666 | pubmed:meshHeading | pubmed-meshheading:1705666-... | lld:pubmed |
| pubmed-article:1705666 | pubmed:meshHeading | pubmed-meshheading:1705666-... | lld:pubmed |
| pubmed-article:1705666 | pubmed:meshHeading | pubmed-meshheading:1705666-... | lld:pubmed |
| pubmed-article:1705666 | pubmed:meshHeading | pubmed-meshheading:1705666-... | lld:pubmed |
| pubmed-article:1705666 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1705666 | pubmed:articleTitle | ELAM-1 is an adhesion molecule for skin-homing T cells. | lld:pubmed |
| pubmed-article:1705666 | pubmed:affiliation | Department of Pathology, Stanford University School of Medicine, California 94305. | lld:pubmed |
| pubmed-article:1705666 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1705666 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:1705666 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:1705666 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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