| pubmed-article:16941345 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16941345 | lifeskim:mentions | umls-concept:C0042776 | lld:lifeskim |
| pubmed-article:16941345 | lifeskim:mentions | umls-concept:C0011311 | lld:lifeskim |
| pubmed-article:16941345 | lifeskim:mentions | umls-concept:C0085274 | lld:lifeskim |
| pubmed-article:16941345 | lifeskim:mentions | umls-concept:C0003320 | lld:lifeskim |
| pubmed-article:16941345 | lifeskim:mentions | umls-concept:C0003316 | lld:lifeskim |
| pubmed-article:16941345 | lifeskim:mentions | umls-concept:C0006933 | lld:lifeskim |
| pubmed-article:16941345 | lifeskim:mentions | umls-concept:C1742737 | lld:lifeskim |
| pubmed-article:16941345 | lifeskim:mentions | umls-concept:C0449450 | lld:lifeskim |
| pubmed-article:16941345 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:16941345 | pubmed:dateCreated | 2006-8-30 | lld:pubmed |
| pubmed-article:16941345 | pubmed:abstractText | For the production of dengue-vaccine candidates, empty capsids, or virus-like particles (VLPs), of parvovirus B19 that carry dengue 2-specific epitopes were employed as antigen carriers. Two epitopes (comprising amino acids 352-368 and 386-397) of domain BIII of the envelope glycoprotein were chosen to produce recombinant B19 VLPs for immunization of BALB/c mice. Serum samples from immunized mice revealed that recombinant B19 VLPs elicited strong humoral immune responses. In summary, this B19 VLP-vaccine platform produced high (> or =2.0 x 10(5)) anti-dengue 2 titers and robust (< or =1 120) 50%-plaque-reduction neutralization test (PRNT(50)) titers, which effectively neutralized live dengue 2 virus in PRNT(50) assays. | lld:pubmed |
| pubmed-article:16941345 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16941345 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16941345 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:16941345 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16941345 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16941345 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16941345 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16941345 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16941345 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:16941345 | pubmed:issn | 0022-1899 | lld:pubmed |
| pubmed-article:16941345 | pubmed:author | pubmed-author:YoungNeal SNS | lld:pubmed |
| pubmed-article:16941345 | pubmed:author | pubmed-author:AmexisGeorgio... | lld:pubmed |
| pubmed-article:16941345 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16941345 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:16941345 | pubmed:volume | 194 | lld:pubmed |
| pubmed-article:16941345 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16941345 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16941345 | pubmed:pagination | 790-4 | lld:pubmed |
| pubmed-article:16941345 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:16941345 | pubmed:meshHeading | pubmed-meshheading:16941345... | lld:pubmed |
| pubmed-article:16941345 | pubmed:meshHeading | pubmed-meshheading:16941345... | lld:pubmed |
| pubmed-article:16941345 | pubmed:meshHeading | pubmed-meshheading:16941345... | lld:pubmed |
| pubmed-article:16941345 | pubmed:meshHeading | pubmed-meshheading:16941345... | lld:pubmed |
| pubmed-article:16941345 | pubmed:meshHeading | pubmed-meshheading:16941345... | lld:pubmed |
| pubmed-article:16941345 | pubmed:meshHeading | pubmed-meshheading:16941345... | lld:pubmed |
| pubmed-article:16941345 | pubmed:meshHeading | pubmed-meshheading:16941345... | lld:pubmed |
| pubmed-article:16941345 | pubmed:meshHeading | pubmed-meshheading:16941345... | lld:pubmed |
| pubmed-article:16941345 | pubmed:meshHeading | pubmed-meshheading:16941345... | lld:pubmed |
| pubmed-article:16941345 | pubmed:meshHeading | pubmed-meshheading:16941345... | lld:pubmed |
| pubmed-article:16941345 | pubmed:meshHeading | pubmed-meshheading:16941345... | lld:pubmed |
| pubmed-article:16941345 | pubmed:meshHeading | pubmed-meshheading:16941345... | lld:pubmed |
| pubmed-article:16941345 | pubmed:meshHeading | pubmed-meshheading:16941345... | lld:pubmed |
| pubmed-article:16941345 | pubmed:meshHeading | pubmed-meshheading:16941345... | lld:pubmed |
| pubmed-article:16941345 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16941345 | pubmed:articleTitle | Parvovirus B19 empty capsids as antigen carriers for presentation of antigenic determinants of dengue 2 virus. | lld:pubmed |
| pubmed-article:16941345 | pubmed:affiliation | Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA. amexis@nih.gov | lld:pubmed |
| pubmed-article:16941345 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16941345 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:16941345 | pubmed:publicationType | Research Support, N.I.H., Intramural | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16941345 | lld:pubmed |
