| pubmed-article:16884882 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16884882 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:16884882 | lifeskim:mentions | umls-concept:C0032105 | lld:lifeskim |
| pubmed-article:16884882 | lifeskim:mentions | umls-concept:C0680730 | lld:lifeskim |
| pubmed-article:16884882 | lifeskim:mentions | umls-concept:C1148554 | lld:lifeskim |
| pubmed-article:16884882 | lifeskim:mentions | umls-concept:C0254211 | lld:lifeskim |
| pubmed-article:16884882 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:16884882 | pubmed:dateCreated | 2006-12-12 | lld:pubmed |
| pubmed-article:16884882 | pubmed:abstractText | A sensitive, specific and accurate method for determination of arbidol in human plasma was developed. Arbidol and internal standard were extracted from plasma samples by liquid-liquid extraction with diethyl ether. The chromatographic separation was accomplished on a Shiseido C18 3 microm analytical column (100 mm x 2.0 mm i.d.) at a flow rate of 0.3 mL/min isocratically. Detection was performed on a single quadrupole mass spectrometer by selected ion monitoring (SIM) mode via electrospray ionization (ESI) source. The method had a chromatographic run time of 6 min and a good linear relationship over the range 1-1000 ng/mL. The limit of quantitation for arbidol in plasma was 1 ng/mL. The intra-day and inter-day precision (R.S.D.%) was lower than 7% and accuracy ranged from 95 to 105%. The proposed method enables unambiguous identification and quantification of arbidol in vivo and has been successfully applied to study the pharmacokinetics of arbidol in healthy male Chinese volunteers. | lld:pubmed |
| pubmed-article:16884882 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16884882 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16884882 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16884882 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16884882 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16884882 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16884882 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16884882 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16884882 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:16884882 | pubmed:issn | 0731-7085 | lld:pubmed |
| pubmed-article:16884882 | pubmed:author | pubmed-author:LiJuanJ | lld:pubmed |
| pubmed-article:16884882 | pubmed:author | pubmed-author:LiuXiaoX | lld:pubmed |
| pubmed-article:16884882 | pubmed:author | pubmed-author:Kai-ShunBiB | lld:pubmed |
| pubmed-article:16884882 | pubmed:author | pubmed-author:HuangYu-WeiYW | lld:pubmed |
| pubmed-article:16884882 | pubmed:author | pubmed-author:ChenXiao-HuiX... | lld:pubmed |
| pubmed-article:16884882 | pubmed:author | pubmed-author:LiXiao-BoXB | lld:pubmed |
| pubmed-article:16884882 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16884882 | pubmed:day | 4 | lld:pubmed |
| pubmed-article:16884882 | pubmed:volume | 43 | lld:pubmed |
| pubmed-article:16884882 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16884882 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16884882 | pubmed:pagination | 371-5 | lld:pubmed |
| pubmed-article:16884882 | pubmed:meshHeading | pubmed-meshheading:16884882... | lld:pubmed |
| pubmed-article:16884882 | pubmed:meshHeading | pubmed-meshheading:16884882... | lld:pubmed |
| pubmed-article:16884882 | pubmed:meshHeading | pubmed-meshheading:16884882... | lld:pubmed |
| pubmed-article:16884882 | pubmed:meshHeading | pubmed-meshheading:16884882... | lld:pubmed |
| pubmed-article:16884882 | pubmed:meshHeading | pubmed-meshheading:16884882... | lld:pubmed |
| pubmed-article:16884882 | pubmed:meshHeading | pubmed-meshheading:16884882... | lld:pubmed |
| pubmed-article:16884882 | pubmed:meshHeading | pubmed-meshheading:16884882... | lld:pubmed |
| pubmed-article:16884882 | pubmed:meshHeading | pubmed-meshheading:16884882... | lld:pubmed |
| pubmed-article:16884882 | pubmed:meshHeading | pubmed-meshheading:16884882... | lld:pubmed |
| pubmed-article:16884882 | pubmed:meshHeading | pubmed-meshheading:16884882... | lld:pubmed |
| pubmed-article:16884882 | pubmed:meshHeading | pubmed-meshheading:16884882... | lld:pubmed |
| pubmed-article:16884882 | pubmed:meshHeading | pubmed-meshheading:16884882... | lld:pubmed |
| pubmed-article:16884882 | pubmed:meshHeading | pubmed-meshheading:16884882... | lld:pubmed |
| pubmed-article:16884882 | pubmed:meshHeading | pubmed-meshheading:16884882... | lld:pubmed |
| pubmed-article:16884882 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:16884882 | pubmed:articleTitle | Determination of arbidol in human plasma by LC-ESI-MS. | lld:pubmed |
| pubmed-article:16884882 | pubmed:affiliation | Department of Pharmaceutical Analysis, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang 110016, China. | lld:pubmed |
| pubmed-article:16884882 | pubmed:publicationType | Journal Article | lld:pubmed |
