pubmed-article:16850759 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:16850759 | lifeskim:mentions | umls-concept:C0021311 | lld:lifeskim |
pubmed-article:16850759 | lifeskim:mentions | umls-concept:C0006852 | lld:lifeskim |
pubmed-article:16850759 | lifeskim:mentions | umls-concept:C0439849 | lld:lifeskim |
pubmed-article:16850759 | lifeskim:mentions | umls-concept:C0963088 | lld:lifeskim |
pubmed-article:16850759 | lifeskim:mentions | umls-concept:C0449438 | lld:lifeskim |
pubmed-article:16850759 | lifeskim:mentions | umls-concept:C0205276 | lld:lifeskim |
pubmed-article:16850759 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
pubmed-article:16850759 | lifeskim:mentions | umls-concept:C0439662 | lld:lifeskim |
pubmed-article:16850759 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
pubmed-article:16850759 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
pubmed-article:16850759 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
pubmed-article:16850759 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:16850759 | pubmed:dateCreated | 2006-7-20 | lld:pubmed |
pubmed-article:16850759 | pubmed:abstractText | To investigate the expression of vaginal IL-23 and its role in experimental murine vaginal candidiasis and its relationship with infection and immune status, immuno-competent (group A) and immuno-suppressed (group B) murine models of vaginal candidiasis were established in estrogen-treated mice. Non-estrogen-treated mice were used as controls (group C). The level of IL-23 p19 mRNA in murine vaginal tissue was determined by RT-PCR. Significantly increased levels of IL-23p19mRNA were observed on the 4th, the 7th and 14th day after inoculation in immuno-competent group when compared with that in control group (P<0.01, P<0.05). However, significant increase of IL-23 p19mRNA were only observed on the 7th day and the 14th day after inoculatuon in immuno-suppressed groups (P<0.05). On the 4th and 7th day, the levels of IL-23 p19mRNA were significantly increased in immuno-competent group than those in immuno-suppressed group (P <0.05). Local IL-23 may play a role in the pathogenesis of murine vaginal candidiasis and has a protective function during infection. Low vaginal IL-23 level may correlate with the increased susceptibility to Candida albicans in immuno-suppressed group. | lld:pubmed |
pubmed-article:16850759 | pubmed:language | eng | lld:pubmed |
pubmed-article:16850759 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16850759 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:16850759 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16850759 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16850759 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:16850759 | pubmed:issn | 1672-0733 | lld:pubmed |
pubmed-article:16850759 | pubmed:author | pubmed-author:RíoLL | lld:pubmed |
pubmed-article:16850759 | pubmed:author | pubmed-author:LiuZhixiangZ | lld:pubmed |
pubmed-article:16850759 | pubmed:author | pubmed-author:LiJiawenJ | lld:pubmed |
pubmed-article:16850759 | pubmed:author | pubmed-author:TanZhijianZ | lld:pubmed |
pubmed-article:16850759 | pubmed:author | pubmed-author:XiaDechaoD | lld:pubmed |
pubmed-article:16850759 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:16850759 | pubmed:volume | 26 | lld:pubmed |
pubmed-article:16850759 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:16850759 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:16850759 | pubmed:pagination | 245-7 | lld:pubmed |
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pubmed-article:16850759 | pubmed:year | 2006 | lld:pubmed |
pubmed-article:16850759 | pubmed:articleTitle | Local IL-23 expression in murine vaginal candidiasis and its relationship with infection and immune status. | lld:pubmed |
pubmed-article:16850759 | pubmed:affiliation | Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. | lld:pubmed |
pubmed-article:16850759 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:16850759 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |