pubmed-article:16848277 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:16848277 | lifeskim:mentions | umls-concept:C0019704 | lld:lifeskim |
pubmed-article:16848277 | lifeskim:mentions | umls-concept:C0237401 | lld:lifeskim |
pubmed-article:16848277 | lifeskim:mentions | umls-concept:C1963724 | lld:lifeskim |
pubmed-article:16848277 | lifeskim:mentions | umls-concept:C0449560 | lld:lifeskim |
pubmed-article:16848277 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:16848277 | pubmed:dateCreated | 2006-7-19 | lld:pubmed |
pubmed-article:16848277 | pubmed:abstractText | The impact of HIV-1 subtype on clinical outcome following exposure to antiretroviral therapy is currently not well known. Natural polymorphisms are often present in HIV-1 non-B subtypes at positions known to be associated with drug resistance in clade B viruses. These changes might influence the emergence of drug-resistant viruses, modifying drug susceptibility and/or the virus replicative capacity. Moreover, different pathways may lead to drug resistance according to HIV-1 clade. Finally, the influence of subtype on the performance of phenotypic assays and in the interpretation of algorithms for genotypic resistance is currently a matter of debate. All these aspects explain why the response to antiretroviral therapy might vary in subjects infected with different HIV-1 clades. | lld:pubmed |
pubmed-article:16848277 | pubmed:language | eng | lld:pubmed |
pubmed-article:16848277 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16848277 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:16848277 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16848277 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16848277 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:16848277 | pubmed:issn | 1139-6121 | lld:pubmed |
pubmed-article:16848277 | pubmed:author | pubmed-author:SorianoVincen... | lld:pubmed |
pubmed-article:16848277 | pubmed:author | pubmed-author:HolguínAfrica... | lld:pubmed |
pubmed-article:16848277 | pubmed:author | pubmed-author:RivasPabloP | lld:pubmed |
pubmed-article:16848277 | pubmed:author | pubmed-author:Ramirez de... | lld:pubmed |
pubmed-article:16848277 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:16848277 | pubmed:volume | 8 | lld:pubmed |
pubmed-article:16848277 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:16848277 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:16848277 | pubmed:pagination | 98-107 | lld:pubmed |
pubmed-article:16848277 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
pubmed-article:16848277 | pubmed:meshHeading | pubmed-meshheading:16848277... | lld:pubmed |
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pubmed-article:16848277 | pubmed:meshHeading | pubmed-meshheading:16848277... | lld:pubmed |
pubmed-article:16848277 | pubmed:articleTitle | Efficacy of antiretroviral therapy in individuals infected with HIV-1 non-B subtypes. | lld:pubmed |
pubmed-article:16848277 | pubmed:affiliation | Department of Infectious Diseases, Hospital Carlos III, Madrid, Spain. aholguin.hciii@salud.madrid.org | lld:pubmed |
pubmed-article:16848277 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:16848277 | pubmed:publicationType | Review | lld:pubmed |
pubmed-article:16848277 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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