| pubmed-article:16809621 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16809621 | lifeskim:mentions | umls-concept:C1028265 | lld:lifeskim |
| pubmed-article:16809621 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:16809621 | lifeskim:mentions | umls-concept:C0332597 | lld:lifeskim |
| pubmed-article:16809621 | lifeskim:mentions | umls-concept:C1521828 | lld:lifeskim |
| pubmed-article:16809621 | lifeskim:mentions | umls-concept:C1517945 | lld:lifeskim |
| pubmed-article:16809621 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:16809621 | pubmed:dateCreated | 2006-8-3 | lld:pubmed |
| pubmed-article:16809621 | pubmed:abstractText | Teleost fishes provide the first unambiguous support for ancient whole-genome duplication in an animal lineage. Studies in yeast or plants have shown that the effects of such duplications can be mediated by a complex pattern of gene retention and changes in evolutionary pressure. To explore such patterns in fishes, we have determined by phylogenetic analysis the evolutionary origin of 675 Tetraodon duplicated genes assigned to chromosomes, using additional data from other species of actinopterygian fishes. The subset of genes, which was retained in double after the genome duplication, is enriched in development, signaling, behavior, and regulation functional categories. The evolutionary rate of duplicate fish genes appears to be determined by 3 forces: 1) fish proteins evolve faster than mammalian orthologs; 2) the genes kept in double after genome duplication represent the subset under strongest purifying selection; and 3) following duplication, there is an asymmetric acceleration of evolutionary rate in one of the paralogs. These results show that similar mechanisms are at work in fishes as in yeast or plants and provide a framework for future investigation of the consequences of duplication in fishes and other animals. | lld:pubmed |
| pubmed-article:16809621 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16809621 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16809621 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16809621 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16809621 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16809621 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:16809621 | pubmed:issn | 0737-4038 | lld:pubmed |
| pubmed-article:16809621 | pubmed:author | pubmed-author:LaudetVincent... | lld:pubmed |
| pubmed-article:16809621 | pubmed:author | pubmed-author:Robinson-Rech... | lld:pubmed |
| pubmed-article:16809621 | pubmed:author | pubmed-author:JaillonOlivie... | lld:pubmed |
| pubmed-article:16809621 | pubmed:author | pubmed-author:BrunetFrédéri... | lld:pubmed |
| pubmed-article:16809621 | pubmed:author | pubmed-author:GibertPatrici... | lld:pubmed |
| pubmed-article:16809621 | pubmed:author | pubmed-author:Roest... | lld:pubmed |
| pubmed-article:16809621 | pubmed:author | pubmed-author:AuryJean-Marc... | lld:pubmed |
| pubmed-article:16809621 | pubmed:author | pubmed-author:ParisMathilde... | lld:pubmed |
| pubmed-article:16809621 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16809621 | pubmed:volume | 23 | lld:pubmed |
| pubmed-article:16809621 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16809621 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16809621 | pubmed:pagination | 1808-16 | lld:pubmed |
| pubmed-article:16809621 | pubmed:dateRevised | 2010-2-17 | lld:pubmed |
| pubmed-article:16809621 | pubmed:meshHeading | pubmed-meshheading:16809621... | lld:pubmed |
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| pubmed-article:16809621 | pubmed:meshHeading | pubmed-meshheading:16809621... | lld:pubmed |
| pubmed-article:16809621 | pubmed:meshHeading | pubmed-meshheading:16809621... | lld:pubmed |
| pubmed-article:16809621 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16809621 | pubmed:articleTitle | Gene loss and evolutionary rates following whole-genome duplication in teleost fishes. | lld:pubmed |
| pubmed-article:16809621 | pubmed:affiliation | Laboratoire de Biologie Moléculaire de la Cellule, INRA LA 1237, CNRS UMR5161, IFR 128 BioSciences Lyon-Gerland, Ecole Normale Supérieure de Lyon, Lyon, France. | lld:pubmed |
| pubmed-article:16809621 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16809621 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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