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pubmed-article:16800022pubmed:abstractTextHighly efficient synthesis of enantiopure diacetates of 2,4-pentanediol and 2,5-hexanediol starting from commercially available mixtures of the diols (dl/meso approximately 1:1) has been realized by combining a fast ruthenium-catalyzed epimerization with an enzymatic transesterification. The in situ coupling of these two processes produces the diacetates in high yield in >99 % enantiomeric excess.lld:pubmed
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pubmed-article:16800022pubmed:dateRevised2009-8-4lld:pubmed
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pubmed-article:16800022pubmed:year2006lld:pubmed
pubmed-article:16800022pubmed:articleTitleHighly efficient synthesis of enantiopure diacetylated C(2)-symmetric diols by ruthenium- and enzyme-catalyzed dynamic kinetic asymmetric transformation (DYKAT).lld:pubmed
pubmed-article:16800022pubmed:affiliationDepartment of Organic Chemistry, Arrhenius Laboratory, Stockholm University, 10691 Stockholm, Sweden.lld:pubmed
pubmed-article:16800022pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:16800022pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed