| pubmed-article:16769253 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16769253 | lifeskim:mentions | umls-concept:C2347782 | lld:lifeskim |
| pubmed-article:16769253 | lifeskim:mentions | umls-concept:C0439849 | lld:lifeskim |
| pubmed-article:16769253 | lifeskim:mentions | umls-concept:C0679823 | lld:lifeskim |
| pubmed-article:16769253 | lifeskim:mentions | umls-concept:C0012802 | lld:lifeskim |
| pubmed-article:16769253 | lifeskim:mentions | umls-concept:C0018720 | lld:lifeskim |
| pubmed-article:16769253 | lifeskim:mentions | umls-concept:C0278329 | lld:lifeskim |
| pubmed-article:16769253 | lifeskim:mentions | umls-concept:C0449774 | lld:lifeskim |
| pubmed-article:16769253 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:16769253 | pubmed:dateCreated | 2006-9-19 | lld:pubmed |
| pubmed-article:16769253 | pubmed:abstractText | The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) published its main findings in December, 2002. It recommended thiazide diuretics as a first-line treatment of hypertension. The current study describes the prescribing patterns of thiazide diuretics in four regions of Kaiser Permanente, a large national United States Health Maintenance Organization--two regions that had an ALLHAT clinical center and two that did not. We tested the hypothesis that participation in a clinical trial leads to quicker and greater adoption of study recommendations than non-participation in a trial. The relative percentage of filled outpatient prescriptions for the period 2 or 3 years before the ALLHAT main publication through December 31, 2004 was calculated by region for thiazide-type diuretics and for calcium channel blockers (CCBs), beta-blockers, central alpha-blockers, angiotensin converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs) and other antihypertensive diuretics. In the 2 years after publication of the ALLHAT trial findings, the percentage of all prescriptions for thiazide diuretics increased from 11.2% to 12.4% in the two regions with an ALLHAT clinical site and from 8.9% to 10.1% in the two regions without an ALLHAT clinical site (p > 0.05). The percentage of new prescriptions for thiazide diuretics increased from 13.7% to 16.6% in the two regions with an ALLHAT clinical site and from 10.8% to 13.0% in the two regions without an ALLHAT clinical site (p > 0.05). Participation in a clinical hypertension study does not appear to accelerate adoption of study recommendations. | lld:pubmed |
| pubmed-article:16769253 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16769253 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16769253 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16769253 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16769253 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16769253 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16769253 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:16769253 | pubmed:issn | 1551-7144 | lld:pubmed |
| pubmed-article:16769253 | pubmed:author | pubmed-author:BarzilayJoshu... | lld:pubmed |
| pubmed-article:16769253 | pubmed:author | pubmed-author:PetittiDiana... | lld:pubmed |
| pubmed-article:16769253 | pubmed:author | pubmed-author:XieFagenF | lld:pubmed |
| pubmed-article:16769253 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16769253 | pubmed:volume | 27 | lld:pubmed |
| pubmed-article:16769253 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16769253 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16769253 | pubmed:pagination | 397-403 | lld:pubmed |
| pubmed-article:16769253 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:16769253 | pubmed:meshHeading | pubmed-meshheading:16769253... | lld:pubmed |
| pubmed-article:16769253 | pubmed:meshHeading | pubmed-meshheading:16769253... | lld:pubmed |
| pubmed-article:16769253 | pubmed:meshHeading | pubmed-meshheading:16769253... | lld:pubmed |
| pubmed-article:16769253 | pubmed:meshHeading | pubmed-meshheading:16769253... | lld:pubmed |
| pubmed-article:16769253 | pubmed:meshHeading | pubmed-meshheading:16769253... | lld:pubmed |
| pubmed-article:16769253 | pubmed:meshHeading | pubmed-meshheading:16769253... | lld:pubmed |
| pubmed-article:16769253 | pubmed:meshHeading | pubmed-meshheading:16769253... | lld:pubmed |
| pubmed-article:16769253 | pubmed:meshHeading | pubmed-meshheading:16769253... | lld:pubmed |
| pubmed-article:16769253 | pubmed:meshHeading | pubmed-meshheading:16769253... | lld:pubmed |
| pubmed-article:16769253 | pubmed:meshHeading | pubmed-meshheading:16769253... | lld:pubmed |
| pubmed-article:16769253 | pubmed:meshHeading | pubmed-meshheading:16769253... | lld:pubmed |
| pubmed-article:16769253 | pubmed:meshHeading | pubmed-meshheading:16769253... | lld:pubmed |
| pubmed-article:16769253 | pubmed:meshHeading | pubmed-meshheading:16769253... | lld:pubmed |
| pubmed-article:16769253 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16769253 | pubmed:articleTitle | Prescribing patterns for thiazide diuretics in a large health maintenance organization: relationship to participation as an ALLHAT clinical center. | lld:pubmed |
| pubmed-article:16769253 | pubmed:affiliation | Kaiser Permanente Southern California, 393 E. Walnut Street, Pasadena, 91188, USA. Diana.b.petitti@kp.org | lld:pubmed |
| pubmed-article:16769253 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16769253 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16769253 | lld:pubmed |
