| pubmed-article:16764541 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16764541 | lifeskim:mentions | umls-concept:C0028953 | lld:lifeskim |
| pubmed-article:16764541 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:16764541 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:16764541 | lifeskim:mentions | umls-concept:C1522492 | lld:lifeskim |
| pubmed-article:16764541 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:16764541 | pubmed:dateCreated | 2006-6-12 | lld:pubmed |
| pubmed-article:16764541 | pubmed:abstractText | During the synthesis of oligonucleotides by the standard phosphoramidite method using 2'-deoxycytidine- derivatized solid support, a side reaction was observed that gave rise to the formation of high molecular weight N-branched oligomers having two identical chains linked to the 3'-terminal 2'-deoxycytidine. Postsynthesis treatment with neat triethylamine trihydrofluoride selectively cleaved the phosphoramidate linkage and converted the N-branched oligomers back to the expected oligonucleotides. | lld:pubmed |
| pubmed-article:16764541 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16764541 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16764541 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16764541 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16764541 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16764541 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16764541 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16764541 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16764541 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16764541 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16764541 | pubmed:issn | 1545-4576 | lld:pubmed |
| pubmed-article:16764541 | pubmed:author | pubmed-author:BathanyKatell... | lld:pubmed |
| pubmed-article:16764541 | pubmed:author | pubmed-author:CazenaveChris... | lld:pubmed |
| pubmed-article:16764541 | pubmed:author | pubmed-author:RaynerBernard... | lld:pubmed |
| pubmed-article:16764541 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16764541 | pubmed:volume | 16 | lld:pubmed |
| pubmed-article:16764541 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16764541 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16764541 | pubmed:pagination | 181-5 | lld:pubmed |
| pubmed-article:16764541 | pubmed:dateRevised | 2009-11-3 | lld:pubmed |
| pubmed-article:16764541 | pubmed:meshHeading | pubmed-meshheading:16764541... | lld:pubmed |
| pubmed-article:16764541 | pubmed:meshHeading | pubmed-meshheading:16764541... | lld:pubmed |
| pubmed-article:16764541 | pubmed:meshHeading | pubmed-meshheading:16764541... | lld:pubmed |
| pubmed-article:16764541 | pubmed:meshHeading | pubmed-meshheading:16764541... | lld:pubmed |
| pubmed-article:16764541 | pubmed:meshHeading | pubmed-meshheading:16764541... | lld:pubmed |
| pubmed-article:16764541 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16764541 | pubmed:articleTitle | Formation of N-branched oligonucleotides as by-products in solid-phase oligonucleotide synthesis. | lld:pubmed |
| pubmed-article:16764541 | pubmed:affiliation | INSERM U386; Université Victor Segalen-Bordeaux 2, 33076 Bordeaux Cedex, France. | lld:pubmed |
| pubmed-article:16764541 | pubmed:publicationType | Journal Article | lld:pubmed |
