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pubmed-article:16761279pubmed:abstractTextX-linked Emery-Dreifuss muscular dystrophy (X-EDMD) is inherited through mutations in EMD, which encodes a nuclear membrane protein named emerin. Emerin is expressed in most cells, but EDMD strikes specific tissues. This review summarizes growing evidence that emerin has roles in both tissue-specific gene regulation and the mechanical integrity of the nucleus and discusses how these roles might impact EDMD.lld:pubmed
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pubmed-article:16761279pubmed:articleTitleMultiple roles for emerin: implications for Emery-Dreifuss muscular dystrophy.lld:pubmed
pubmed-article:16761279pubmed:affiliationDepartment of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.lld:pubmed
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