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pubmed-article:16757497pubmed:abstractTextSera of IgA nephropathy (IgAN) patients contain high levels of circulating immune complexes composed of IgA1 molecules with aberrantly glycosylated hinge-region O-linked oligosaccharides and IgG or IgA1 antibodies with anti-glycan or anti-hinge-region peptide specificities. Due to damaged sieving properties of the glomerular capillary wall in IgAN, these immune complexes may appear in the urine.lld:pubmed
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pubmed-article:16757497pubmed:articleTitleIgA-containing immune complexes in the urine of IgA nephropathy patients.lld:pubmed
pubmed-article:16757497pubmed:affiliationDepartment of Microbiology, University of Alabama at Birmingham, 845 19th Street South, Birmingham, AL 35294-2170, USA. kmatousovic@hotmail.comlld:pubmed
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