| pubmed-article:16741960 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16741960 | lifeskim:mentions | umls-concept:C0043047 | lld:lifeskim |
| pubmed-article:16741960 | lifeskim:mentions | umls-concept:C0009325 | lld:lifeskim |
| pubmed-article:16741960 | lifeskim:mentions | umls-concept:C0596957 | lld:lifeskim |
| pubmed-article:16741960 | lifeskim:mentions | umls-concept:C0994334 | lld:lifeskim |
| pubmed-article:16741960 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:16741960 | lifeskim:mentions | umls-concept:C0332162 | lld:lifeskim |
| pubmed-article:16741960 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:16741960 | pubmed:dateCreated | 2006-8-21 | lld:pubmed |
| pubmed-article:16741960 | pubmed:abstractText | The onset of water gelation around a collagen-like triple helix peptide was studied at ambient temperature and pressure by performing Molecular Dynamics simulations. The radial distribution functions of the oxygen and hydrogen atoms of water are distorted below 4 A from the peptide. The distortion is accompanied by the breakdown of the tetrahedral coordination of the hydrogen-bonded network of water molecules. The water shell around the peptide consists of alternating regions of higher and lower density. In agreement with experiments we find that the first hydration shell is kinetically labile, with a residence time in the order of picoseconds for a water molecule. From the computed diffusion coefficient, a key measure of the collective dynamics, we estimate the average diffusion speed decreases by a factor of 1.5 close to the peptide compared to the liquid. Our results give new insight in gel formation and structure on a molecular level. | lld:pubmed |
| pubmed-article:16741960 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16741960 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16741960 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16741960 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16741960 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16741960 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16741960 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16741960 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16741960 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:16741960 | pubmed:issn | 1097-0134 | lld:pubmed |
| pubmed-article:16741960 | pubmed:author | pubmed-author:ZerbettoFranc... | lld:pubmed |
| pubmed-article:16741960 | pubmed:author | pubmed-author:HandgraafJan-... | lld:pubmed |
| pubmed-article:16741960 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:16741960 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:16741960 | pubmed:volume | 64 | lld:pubmed |
| pubmed-article:16741960 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16741960 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16741960 | pubmed:pagination | 711-8 | lld:pubmed |
| pubmed-article:16741960 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:16741960 | pubmed:meshHeading | pubmed-meshheading:16741960... | lld:pubmed |
| pubmed-article:16741960 | pubmed:meshHeading | pubmed-meshheading:16741960... | lld:pubmed |
| pubmed-article:16741960 | pubmed:meshHeading | pubmed-meshheading:16741960... | lld:pubmed |
| pubmed-article:16741960 | pubmed:meshHeading | pubmed-meshheading:16741960... | lld:pubmed |
| pubmed-article:16741960 | pubmed:meshHeading | pubmed-meshheading:16741960... | lld:pubmed |
| pubmed-article:16741960 | pubmed:meshHeading | pubmed-meshheading:16741960... | lld:pubmed |
| pubmed-article:16741960 | pubmed:meshHeading | pubmed-meshheading:16741960... | lld:pubmed |
| pubmed-article:16741960 | pubmed:meshHeading | pubmed-meshheading:16741960... | lld:pubmed |
| pubmed-article:16741960 | pubmed:meshHeading | pubmed-meshheading:16741960... | lld:pubmed |
| pubmed-article:16741960 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16741960 | pubmed:articleTitle | Molecular dynamics study of onset of water gelation around the collagen triple helix. | lld:pubmed |
| pubmed-article:16741960 | pubmed:affiliation | Dipartimento di Chimica G. Ciamician, Università di Bologna, Via F. Selmi 2, 40126 Bologna, Italy. j.w.handgraaf@chem.leidenuniv.nl | lld:pubmed |
| pubmed-article:16741960 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16741960 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
