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pubmed-article:16598383pubmed:abstractTextA novel role for IGF-I in MSC chondrogenesis was determined. IGF-I effects were evaluated in the presence or absence of TGF-beta signaling by conditionally inactivating the TGF-beta type II receptor. We found that IGF-I had potent chondroinductive actions on MSCs. IGF-I effects were independent from and additive to TGF-beta.lld:pubmed
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pubmed-article:16598383pubmed:articleTitleEffect of IGF-I in the chondrogenesis of bone marrow mesenchymal stem cells in the presence or absence of TGF-beta signaling.lld:pubmed
pubmed-article:16598383pubmed:affiliationDepartment of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-2579, USA.lld:pubmed
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