This study was undertaken to investigate the presence of autoantibodies against the main cartilage proteoglycan, aggrecan, in systemic rheumatic disease sera, and to identify substructure(s) responsible for the autoimmune response.
Laboratory of Biochemistry, Department of Chemistry, School of Natural Sciences, University of Patras, 26500 Rio, Patras, Greece. vynios@chemistry.upatras.gr
