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pubmed-article:16446333pubmed:abstractTextThe treatment of early-stage Hodgkin's disease (HD) has evolved from radiotherapy alone (RT) to combined-modality therapy (CMT) because of concerns about late adverse effects from high-dose subtotal nodal irradiation (STNI). However, there is little information regarding the long-term results of CMT programs that substantially reduce the dose and extent of radiation. In addition, lowering the total radiation dose may reduce the complication rate without compromising cure. This retrospective study compares the long-term results of STNI with CMT using modestly reduced RT dose in the treatment of early-stage HD.lld:pubmed
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pubmed-article:16446333pubmed:year2006lld:pubmed
pubmed-article:16446333pubmed:articleTitleCombined-modality therapy versus radiotherapy alone for treatment of early-stage Hodgkin's disease: cure balanced against complications.lld:pubmed
pubmed-article:16446333pubmed:affiliationDepartment of Radiation Oncology, Department of Medicine, Division of Medical Oncology, Duke University Medical Center, Durham, NC 27710, USA. koont005@radonc.duke.edulld:pubmed
pubmed-article:16446333pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:16446333pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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