| pubmed-article:1643160 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1643160 | lifeskim:mentions | umls-concept:C0005821 | lld:lifeskim |
| pubmed-article:1643160 | lifeskim:mentions | umls-concept:C0857305 | lld:lifeskim |
| pubmed-article:1643160 | lifeskim:mentions | umls-concept:C0162595 | lld:lifeskim |
| pubmed-article:1643160 | lifeskim:mentions | umls-concept:C0443146 | lld:lifeskim |
| pubmed-article:1643160 | lifeskim:mentions | umls-concept:C1145667 | lld:lifeskim |
| pubmed-article:1643160 | lifeskim:mentions | umls-concept:C0332240 | lld:lifeskim |
| pubmed-article:1643160 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:1643160 | pubmed:dateCreated | 1992-9-10 | lld:pubmed |
| pubmed-article:1643160 | pubmed:abstractText | We recently reported that IgM antibody-related microparticles exist in some patients with idiopathic thrombocytopenic purpura (ITP) [14]. In this study, we investigated the relationship between antiphospholipid (cardiolipin and phosphatidylinositol) antibodies and microparticles in 56 ITP patients. We used an ELISA to detect anti-phospholipid antibodies. IgG antibodies against cardiolipin and phosphatidylinositol were detected in 13 and 12 patients, respectively. The titers of IgG antibodies against these phospholipids did not correlate with the platelet-associated IgG level or the platelet count. Next, we investigated the binding of anti-phospholipid antibodies to platelets and microparticles. Microparticles were obtained by incubating washed platelets with collagen plus thrombin. ITP plasma containing IgG-class anti-phospholipid antibodies showed significantly increase binding to microparticles compared with plasma without such antibodies (p less than 0.001). Our results suggest that anti-phospholipid antibodies could affect the function of platelet microparticles in ITP. | lld:pubmed |
| pubmed-article:1643160 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1643160 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1643160 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1643160 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1643160 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1643160 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1643160 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:1643160 | pubmed:issn | 0939-5555 | lld:pubmed |
| pubmed-article:1643160 | pubmed:author | pubmed-author:YamaguchiKK | lld:pubmed |
| pubmed-article:1643160 | pubmed:author | pubmed-author:SuzukiMM | lld:pubmed |
| pubmed-article:1643160 | pubmed:author | pubmed-author:KidoHH | lld:pubmed |
| pubmed-article:1643160 | pubmed:author | pubmed-author:NomuraSS | lld:pubmed |
| pubmed-article:1643160 | pubmed:author | pubmed-author:YasunagaKK | lld:pubmed |
| pubmed-article:1643160 | pubmed:author | pubmed-author:KokawaTT | lld:pubmed |
| pubmed-article:1643160 | pubmed:author | pubmed-author:KawakatsuTT | lld:pubmed |
| pubmed-article:1643160 | pubmed:author | pubmed-author:FukuroiTT | lld:pubmed |
| pubmed-article:1643160 | pubmed:author | pubmed-author:YanabuMM | lld:pubmed |
| pubmed-article:1643160 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1643160 | pubmed:volume | 65 | lld:pubmed |
| pubmed-article:1643160 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1643160 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1643160 | pubmed:pagination | 46-9 | lld:pubmed |
| pubmed-article:1643160 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:1643160 | pubmed:meshHeading | pubmed-meshheading:1643160-... | lld:pubmed |
| pubmed-article:1643160 | pubmed:meshHeading | pubmed-meshheading:1643160-... | lld:pubmed |
| pubmed-article:1643160 | pubmed:meshHeading | pubmed-meshheading:1643160-... | lld:pubmed |
| pubmed-article:1643160 | pubmed:meshHeading | pubmed-meshheading:1643160-... | lld:pubmed |
| pubmed-article:1643160 | pubmed:meshHeading | pubmed-meshheading:1643160-... | lld:pubmed |
| pubmed-article:1643160 | pubmed:meshHeading | pubmed-meshheading:1643160-... | lld:pubmed |
| pubmed-article:1643160 | pubmed:meshHeading | pubmed-meshheading:1643160-... | lld:pubmed |
| pubmed-article:1643160 | pubmed:meshHeading | pubmed-meshheading:1643160-... | lld:pubmed |
| pubmed-article:1643160 | pubmed:meshHeading | pubmed-meshheading:1643160-... | lld:pubmed |
| pubmed-article:1643160 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1643160 | pubmed:articleTitle | Anti-phospholipid antibodies bind to platelet microparticles in idiopathic (autoimmune) thrombocytopenic purpura. | lld:pubmed |
| pubmed-article:1643160 | pubmed:affiliation | First Department of Internal Medicine, Kansai Medical University, Osaka, Japan. | lld:pubmed |
| pubmed-article:1643160 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1643160 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1643160 | lld:pubmed |
