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pubmed-article:16431305pubmed:abstractTextCommon treatment practices in patients who continue to be symptomatic on proton pump inhibitor once-daily treatment include either increasing the dosage or the use of supplemental medication. This trial's purpose was to compare 2 therapeutic strategies, increasing the proton pump inhibitor dosage to twice daily versus switching to another proton pump inhibitor, in patients with persistent heartburn while receiving standard-dose proton pump inhibitor therapy.lld:pubmed
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pubmed-article:16431305pubmed:articleTitleTreatment of patients with persistent heartburn symptoms: a double-blind, randomized trial.lld:pubmed
pubmed-article:16431305pubmed:affiliationThe Neuro-Enteric Clinical Research Group, Department of Medicine, Section of Gastroenterology, Southern Arizona VA Health Care System and University of Arizona Health Sciences Center, Tucson 85723-0001, USA. Ronnie.Fass@med.VA.govlld:pubmed
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