| pubmed-article:16397778 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16397778 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:16397778 | lifeskim:mentions | umls-concept:C0022650 | lld:lifeskim |
| pubmed-article:16397778 | lifeskim:mentions | umls-concept:C2700116 | lld:lifeskim |
| pubmed-article:16397778 | lifeskim:mentions | umls-concept:C0044481 | lld:lifeskim |
| pubmed-article:16397778 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:16397778 | pubmed:dateCreated | 2006-2-10 | lld:pubmed |
| pubmed-article:16397778 | pubmed:abstractText | An unusual case with kidney stones composed mainly of 1-methyluric acid is described. The patient, a Caucasian male of Celtic descent, reportedly drank at least eight cups of coffee per day and had a long history of rheumatoid arthritis, gouty attacks and renal colics--the latter attributed to nephrocalcinosis and analgesic nephropathy. He was treated with allopurinol. At 54 years, a bilateral nephrolithotomy was performed. Stone samples were analysed by thermogravimetry and infrared spectroscopy and reported to be 12-25% calcium oxalate, the remainder being organic uric acid-like material. Analysis of the extracts by HPLC confirmed that the organic material contained 67% of 1-methyluric acid and 33% of uric acid. Possible mechanisms leading to the precipitation of 1-methyluric acid from urine are discussed. We conclude that the high caffeine intake resulted in extremely elevated urinary concentrations of 1-methyluric acid favouring the formation of 1-methyluric acid stones. | lld:pubmed |
| pubmed-article:16397778 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16397778 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16397778 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16397778 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16397778 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16397778 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16397778 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16397778 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16397778 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16397778 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:16397778 | pubmed:issn | 0300-5623 | lld:pubmed |
| pubmed-article:16397778 | pubmed:author | pubmed-author:FairbanksLyne... | lld:pubmed |
| pubmed-article:16397778 | pubmed:author | pubmed-author:SimmondsH... | lld:pubmed |
| pubmed-article:16397778 | pubmed:author | pubmed-author:SafranowKrzys... | lld:pubmed |
| pubmed-article:16397778 | pubmed:author | pubmed-author:DaviesPhillip... | lld:pubmed |
| pubmed-article:16397778 | pubmed:author | pubmed-author:BendingMichae... | lld:pubmed |
| pubmed-article:16397778 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16397778 | pubmed:volume | 34 | lld:pubmed |
| pubmed-article:16397778 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16397778 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16397778 | pubmed:pagination | 58-60 | lld:pubmed |
| pubmed-article:16397778 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:16397778 | pubmed:meshHeading | pubmed-meshheading:16397778... | lld:pubmed |
| pubmed-article:16397778 | pubmed:meshHeading | pubmed-meshheading:16397778... | lld:pubmed |
| pubmed-article:16397778 | pubmed:meshHeading | pubmed-meshheading:16397778... | lld:pubmed |
| pubmed-article:16397778 | pubmed:meshHeading | pubmed-meshheading:16397778... | lld:pubmed |
| pubmed-article:16397778 | pubmed:meshHeading | pubmed-meshheading:16397778... | lld:pubmed |
| pubmed-article:16397778 | pubmed:meshHeading | pubmed-meshheading:16397778... | lld:pubmed |
| pubmed-article:16397778 | pubmed:meshHeading | pubmed-meshheading:16397778... | lld:pubmed |
| pubmed-article:16397778 | pubmed:meshHeading | pubmed-meshheading:16397778... | lld:pubmed |
| pubmed-article:16397778 | pubmed:meshHeading | pubmed-meshheading:16397778... | lld:pubmed |
| pubmed-article:16397778 | pubmed:meshHeading | pubmed-meshheading:16397778... | lld:pubmed |
| pubmed-article:16397778 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16397778 | pubmed:articleTitle | An unusual patient with kidney stones composed of 1-methyluric acid. | lld:pubmed |
| pubmed-article:16397778 | pubmed:affiliation | Purine Research Unit, 5th Floor Thomas Guy House, Guy's Hospital, SE1 9RT, London Bridge, UK. | lld:pubmed |
| pubmed-article:16397778 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16397778 | pubmed:publicationType | Case Reports | lld:pubmed |
