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pubmed-article:16310510pubmed:abstractTextPatients with bipolar disorder have been reported to have abnormal cortical function during mania. In this study, we sought to investigate neural activity in the frontal lobe during mania, using functional magnetic resonance imaging (fMRI). Specifically, we sought to evaluate activation in the lateral orbitofrontal cortex, a brain region that is normally activated during activities that require response inhibition.lld:pubmed
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pubmed-article:16310510pubmed:articleTitleBlunted activation in orbitofrontal cortex during mania: a functional magnetic resonance imaging study.lld:pubmed
pubmed-article:16310510pubmed:affiliationDepartment of Psychiatry, Los Angeles, California, USA. laltshuler@mednet.ucla.edulld:pubmed
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